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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · Colloidal dosage forms have been widely studied and employed in the field of ocular drug delivery . These dosage forms include liposomes, nanoparticles, microemulsions, and nanoemulsions etc. Barriers to ocular drug delivery have already been described earlier in the context of structure and function of various ocular tissues and how each ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
Conventional dosage forms such as eye drops account for 90% of the marketed ophthalmic formulations. ... It is emerged as promising strategy for delivery of hydrophobic drugs. For ocular delivery, it provides several advantages such as ... Thermoresponsive hydrogels as a new ocular drug delivery platform to the posterior segment of the eye ...Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
https://www.researchgate.net/profile/Sudip_Das4/publication/279418971_Microparticles_and_Nanoparticles_in_Ocular_Drug_Delivery/links/5b8cd0e3299bf1d5a73a0ba4/Microparticles-and-Nanoparticles-in-Ocular-Drug-Delivery.pdf
ophthalmic drug delivery technique that may enhance dosage form accept- ability while providing sustained release in the ocular milieu (14). Particulate drug delivery consists of systems described ...
https://link.springer.com/article/10.1023%2FA%3A1011989202488
Sep 01, 1998 · Purpose. The main goal of this study was to develop an ocular controlled release formulation of a model oligonucleotide (pdT16), contained within liposomes dispersed within a thermosensitive gel composed by poloxamer 407. Methods. The influence of the poloxamer concentration 2% or 27% on the stability of the liposomes (PC: CHOL and PC: CHOL: PEG-DSPE) was …Author: Amélie Bochot, Elias Fattal, Annette Gulik, Guy Couarraze, Patrick Couvreur
https://www.hindawi.com/journals/tswj/2014/861904/
This paper describes hitherto developed drug forms for topical ocular administration, that is, eye drops, ointments, in situ gels, inserts, multicompartment drug delivery systems, and ophthalmic drug forms with bioadhesive properties. Heretofore, many studies have demonstrated that new and more complex ophthalmic drug forms exhibit advantage over traditional ones and are able to increase the ...Author: Przemysław Baranowski, Bożena Karolewicz, Maciej Gajda, Janusz Pluta
https://www.sciencedirect.com/science/article/pii/0169409X9500012V
Within the last few decades, in response to the advent of potent and versatile therapeutic agents, the diversity of conventional ophthalmic formulations has gradually evolved, extending well beyond simple solutions, and now includes a variety of types of drug administration.Author: John C. Lang
https://www.ondrugdelivery.com/optimising-ophthalmic-drug-delivery-for-therapeutic-effectiveness/
“The ocular pharma industry is experiencing an unprecedented surge in venture capital investment, innovation and new drug and biologic approvals.” Dosage form options are diverse, ranging from topical emulsions, suspension, and solutions to injectables and implants, as are the formulation options and delivery considerations for each.
http://ijpsr.com/bft-article/novel-drug-delivery-systems-an-overview/?view=fulltext
ABSTRACT: Evolution of an existing drug molecule from a conventional form to a novel delivery system can significantly improve its performance in terms of patient compliance, safety and efficacy.In the form of a Novel Drug Delivery System an existing drug molecule can get a new life. An appropriately designed Novel Drug Delivery System can be a major advance for solving the problems related ...
https://journals.sagepub.com/doi/pdf/10.1177/0192623307310955
implantable prolonged-action dosage forms (Figure 3). ... of new technologies in ocular drug delivery and new drug can-didates, including biologics, to treat these challenging diseases ... form of ocular medication, is less than 5% and often less than 1%, and therefore, only the …
https://www.researchgate.net/publication/285996401_AN_UPDATE_REVIEW_ON_NOVEL_ADVANCED_OCULAR_DRUG_DELIVERY_SYSTEM
AN UPDATE REVIEW ON NOVEL ADVANCED OCULAR DRUG DELIVERY SYSTEM. ... form may reduce w ith new drug delivery s ystem. ... microemulsions are a promising dosage form for …
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