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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465129/
The delivery of vaccines or drugs is not by diffusion as in transdermal delivery systems but by a temporary mechanical disruption of the skin leading to the placement of the drug or vaccine within the epidermis, where it can more readily reach its site of action.
https://www.pharmacytimes.com/publications/supplements/2019/august2019/new-vaccines-in-the-pipeline-2019
New Delivery Systems Combination vaccines are advantageous because they mitigate the burden of multiple injections, reduce the number of visits, and save on costs for storage and shipment. 20 In 2018, the FDA approved a new hexavalent vaccine, DTaP5-HB-IPV- Hib (Vaxelis, Merck) for primary and booster vaccination in infants and toddlers against ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024302/
Two basic delivery approaches including physical delivery to achieve higher levels of antigen production and formulation with microparticles to target antigen-presenting cells (APCs) have demonstrated to be effective in animal models. New developments in vaccine delivery systems will improve the efficiency of clinical trials in the near future.Author: Azam Bolhassani, Shima Safaiyan, Sima Rafati
https://www.sciencedirect.com/science/article/pii/S0264410X08003915
These drawbacks, and the development of new types of vaccines, are some of the reasons driving the pharmaceutical industry and public health organizations to search for new delivery methods that are safe, cost-effective and efficient.Author: Paul Henri Lambert, Philippe E. Laurent
http://news.mit.edu/2019/rna-vaccine-delivery-0930
Sep 30, 2019 · MIT chemical engineers have developed a new type of lipid nanoparticle that can be used to deliver RNA vaccines. The particles also trigger the release of powerful immune signaling proteins that boost the vaccines’ effectiveness.
https://www.pfizer.com/partners/candidate/vaccines
Over the years, we’ve played a pivotal role in eliminating or nearly eliminating deadly infectious diseases like smallpox and polio globally. We have designed novel vaccines based on new delivery systems and technologies that have resulted in vaccines to prevent bacterial infections, like those caused by S. pneumoniae and N. meningitidis.
https://www.researchgate.net/publication/232257539_Recent_trends_in_vaccine_delivery_systems_A_review
Recent trends in vaccine delivery systems: A review ... plant-derived viruses which are now being investigated and developed as vaccine delivery systems. This paper also describes various aspects ...
https://journals.sagepub.com/doi/10.1177/2051013614541440
Jul 11, 2014 · Liposomes as vaccine delivery systems: a review of the recent advances ... Liposomes as vaccine delivery systems: a review of the recent advances Show all authors. Reto A. Schwendener. ... The enormous versatility of liposomes and the related archaeosomes and virosomes endows them as highly valuable carrier systems for vaccines. Besides ...Author: Reto A. Schwendener
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