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https://www.nature.com/articles/nrd.2018.183
Nov 30, 2018 · A review of advanced oral drug delivery technologies facilitating the protection and absorption of protein and peptide molecules. Biotechnol. Adv. 32 , 1269–1282 (2014).Author: Aaron C. Anselmo, Yatin Gokarn, Samir Mitragotri
https://www.nature.com/articles/s41573-019-0012-9
Feb 01, 2019 · Adeno-associated virus (AAV) vectors are the leading platform for gene delivery for the treatment of a variety of human diseases. Recent advances in …Author: Dan Wang, Phillip W. L. Tai, Guangping Gao
http://feeds.nature.com/nrd/rss/aop?year=2019
This Review highlights the challenges of using mouse models to advance drug discovery in Alzheimer disease, discussing the emerging opportunities to optimize disease modelling and alternative preclinical research systems to test therapeutic approaches in this highly prevalent disease.
https://www.ncbi.nlm.nih.gov/pubmed/28337020
However, for each of these systems to effectively enter cells of interest and perform their function, efficient and safe delivery technologies are needed. This Review discusses the principles of biomacromolecule delivery and gene editing, examines recent advances and challenges in non-viral and viral delivery methods, and highlights the status ...Author: Hao Yin, Kevin J. Kauffman, Daniel G. Anderson
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Drug delivery and nanoparticles: Applications and hazards. ... their dendritic nature and branching allows for drug loading onto the outside surfaces of the polymeric structure ... Mader K, Gohla S. Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art. Eur J …Author: Wim H De Jong, Paul Ja Borm
http://feeds.nature.com/nrd/rss/aop?type=online-correspondence
Mar 19, 2020 · nature; nature reviews drug discovery; browse articles; A Nature Research Journal ... in which sickled red blood cells clump together, blocking blood flow and the delivery of oxygen through the body, afflicts nearly 100,000 people in the USA and millions more throughout the world. ... This Review discusses how proteomic technologies are ...
https://www.journals.elsevier.com/advanced-drug-delivery-reviews/most-downloaded-articles
Jul 25, 2009 · Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25.1
https://www.journals.elsevier.com/advanced-drug-delivery-reviews/
Articles review the current status of a specific topic, giving equal emphasis to the identification of major conceptual and technological challenges to successful drug and gene delivery, to an evaluation of triumphs as well as shortcomings in current conceptual and technical approaches, and to a discussion of their possible solution.
https://www.sciencedirect.com/science/article/pii/S0168365918302700
Surprisingly, nature has provided some exciting materials called diatoms; biosilica is one such a material that can be potentially used as a drug delivery vehicle. The present review focuses on different types of diatom species used in drug delivery with respect to their structural properties, morphology, purification process and surface ...Author: U.T. Uthappa, Varsha Brahmkhatri, G. Sriram, Ho-Young Jung, Jingxian Yu, Nikita Kurkuri, Tejraj M. A...
https://chemistrycommunity.nature.com/users/345661-idil-cazimoglu/posts/58516-controlled-release
Feb 18, 2020 · Multi-compartment drug delivery systems have the potential to carry out internal reactions and release the products, if molecule transport can be controlled. We have developed a system to activate a pro-drug analog in-situ and release it upon demand, through a …
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