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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787057/
INHALED INSULIN. Insulin delivery to the lungs was the first reported alternate to subcutaneous injection. It has long been appreciated that insulin delivery by aerosol reduces blood glucose.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539067/
Oct 18, 2012 · The ViaNase device has been used to deliver nasal insulin in patients with early Alzheimer’s disease (AD), and clinical benefit has been demonstrated [74, 75]. In these studies, delivery of insulin was performed over a 2-min period by nasal inhalation.Author: Per Gisle Djupesland
https://www.lostfalco.com/intranasal-insulin/
“Saline or insulin (Novolin R; Novo Nordisk, Princeton, New Jersey) was administered after breakfast and dinner with a ViaNase nasal drug delivery device…” Here’s the ViaNase. While something like the ViaNase might be nice other human studies on intranasal insulin have used spray bottles or droppers with very good results.
https://www.sciencedirect.com/science/article/pii/S0169409X98000738
Intranasal insulin delivery has been widely investigated as an alternative to subcutaneous injection for the treatment of diabetes. The pharmacokinetic profile of intranasal insulin is similar to that obtained by intravenous injection and, in contrast to subcutaneous insulin delivery, bears close resemblance to the `pulsatile' pattern of endogenous insulin secretion during meal-times.Author: Michael Hinchcliffe, Lisbeth Illum
https://www.alzforum.org/therapeutics/nasal-insulin
In September 2013, the Alzheimer's Disease Cooperative study began enrolling for Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF), a federally funded study that is to deliver 20 IU of insulin or placebo after breakfast and dinner to 240 people with either aMCI or …
https://www.nia.nih.gov/alzheimers/clinical-trials/study-nasal-insulin-fight-forgetfulness-sniff
26 rows · The study uses intranasal administration focusing on nose-to-brain transport as a mode of …
https://www.sciencedirect.com/science/article/pii/S135964461830254X
Nasal insulin delivery CPEX Pharmaceuticals Inc. has developed an intranasal insulin spray, containing regular short-acting human recombinant insulin, and given the trade name Nasulin™. The main excipient in the nasal insulin formulation is cyclopentadecalactone (CPE-215), which, according to the company, has been proven to enhance absorption 71 , 72 .Author: Najma Easa, Raid G. Alany, Mark Carew, Anil Vangala
https://www.webmd.com/diabetes/inhaled-insulin
Inhaled insulin is another option for people with diabetes to control their blood sugar. It works for both type 1 and type 2 diabetes, but you shouldn't use it if you smoke or have asthma or COPD ...
https://www.webmd.com/diabetes/news/20151218/nasal-spray-may-give-diabetics-faster-treatment-for-low-blood-sugar
Dec 18, 2015 · The nasal spray contains powdered glucagon, a hormone that causes a prompt increase in blood sugar levels. The trial results showed that the nasal spray is nearly as effective in treating hypoglycemia (low blood sugar) as the only option currently available, a glucagon powder...
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