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https://www.technologyreview.com/s/409737/nanovalves-for-drug-delivery/
Mar 13, 2008 · A new nanovalve that opens in response to pH changes could serve as the basis of a targeted drug delivery system. By filling a tiny, porous silica sphere with a …Author: Jocelyn Rice
https://www.sciencedirect.com/science/article/pii/S259023851930044X
There is a growing demand for smart drug-delivery systems to meet the complicated requirements in biomedical applications. Supramolecular nanovalves have been used to regulate the transportation of drug molecules by reversible linkage of multiple components, which have paved an advanced way to construct gated materials for controlled drug release.Author: Zheng Li, Nan Song, Ying-Wei Yang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327898/
Jan 21, 2015 · A multifunctional mesoporous drug delivery system that contains fluorescent imaging molecules, targeting proteins, and pH-sensitive nanovalves was developed and tested. Three nanovalve-MSN systems (NV-MSNs) with varied quantities of nanovalves on the ...Author: Angela A. Hwang, Jie Lu, Fuyuhiko Tamanoi, Jeffrey I. Zink
https://www.sciencedirect.com/science/article/pii/S1387181111002885
A biocompatible pH-responsive drug delivery nanovalve system was designed, synthesized, and tested. The on-command pH-activated system displayed very good stability—no drug leakage at pH ∼7.4 and excellent drug release performance not only in H 2 O but also in cell culture medium at pH ∼5.5. Download : Download full-size imageAuthor: Li Du, Huiyu Song, Shijun Liao
https://www.nature.com/articles/s41392-017-0004-3
Mar 16, 2018 · The drug delivery platform based on mechanized silica nanoparticles (MSNPs), which consists of MSNs vehicles, acid-cleavage intermediate linkages and reversible supramolecular nanovalves, was ...Author: Sudipta Senapati, Arun Kumar Mahanta, Sunil Kumar, Pralay Maiti
https://www.cell.com/matter/pdf/S2590-2385(19)30044-X.pdf
drug delivery, which not only endow the delivery systems with flexible and robust ... lecular nanovalves could be switched on and off, triggered by external stimuli including light irradiation, pH, thermal, redox, competitive binding, magnetic field,
http://onlinelibrary.wiley.com/doi/10.1002/smll.201400765/full
A multifunctional mesoporous drug delivery system that contains fluorescent imaging molecules, targeting proteins, and pH‐sensitive nanovalves is developed and tested. Three nanovalve‐mesoporous silica nanoparticle (NV‐MSN) systems with varied quantities of nanovalves on the surface are synthesized.
https://www.researchgate.net/publication/311941829_Nanorobotics_in_Drug_Delivery_Systems_for_Treatment_of_Cancer_A_Review
Nanorobotics in Drug Delivery Systems for Treatment of Cancer: A Review ... It has an eminence future in the drug delivery technology target in cancer, the disease that leading cause of death ...
https://www.researchgate.net/publication/335045195_Stimuli-Responsive_Drug-Delivery_Systems_Based_on_Supramolecular_Nanovalves
Significantly, pillararene-based pseudorotaxanes as pH/temperature dual-responsive nanovalves allow targeted drug delivery in pathological environment with sustained release over 4 days, which is ...
https://onlinelibrary.wiley.com/doi/abs/10.1002/smll.201400042
After incubation of the nanosystem with MCF‐7 breast cancer cells, two‐photon irradiation at low power is used to image the cells. At high power, cancer cell killing is observed due to the two‐photon‐triggered opening of the pores through FRET and the release of the anticancer drug from the MSN.Author: Jonas Croissant, Arnaud Chaix, Arnaud Chaix, Olivier Mongin, Miao Wang, Sébastien Clément, Laurence ...
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