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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639314/
Nanoscale Drug Delivery Systems for Enhanced Drug Penetration into Solid Tumors: Current Progress and Opportunities Carolyn L. Waite a and Charles M. Roth a, b, * a Department of Chemical and Biochemical Engineering, Rutgers University, New Brunswick, New JerseyAuthor: Carolyn L. Waite, Charles M. Roth
https://www.asme.org/topics-resources/content/4-innovations-in-nanoscale-drug-delivery
Nanoscale drug delivery is allowing doctors and scientists to target specific areas of the body for treatment—lowering the amount of medicine given and its side effects.
https://pubs.rsc.org/en/content/articlelanding/2012/nr/c2nr11606e#!
Delivery across skin offers many advantages compared to oral or intravenous routes of drug administration. Skin however is highly impermeable to most molecules on the basis of size, hydrophilicity, lipophilicity and charge. For this reason it is often necessary to temporarily alter the barrier properties of
http://www.onecentralpress.com/wp-content/uploads/2014/11/CHAPTER-8-NB-30-LATEST.pdf
nanomaterials as drug delivery platforms, it may be possible to achieve improved delivery of poorly water-soluble drugs thereby increasing their bioavailability in the biological systems [6,7]. Another unique feature of nanomaterial based drug delivery is their ability to achieve targeted delivery of drugs in cell or tissue specific manner [8].
https://edgy.app/nanoscale-biodegradable-bottles-for-targeted-drug-delivery
Aug 20, 2019 · Targeted drug delivery, or smart drug delivery, is a sophisticated technology that carries medicine to the desired diseased organs or tissues within the body. Decades of research are leading to the development of targeted drug delivery as a valuable tool in pharmaceutical therapies. Biomedical and chemical engineers are exploring many ...
https://www.sciencedirect.com/science/article/pii/S0304383516303366
Nanoscale drug delivery systems for tumor targeting are based on the delivery of anti-tumor drugs within nanocarriers capable of targeting tumor tissues by taking advantage of the physiological and pathological characteristics of tumors .Author: Yong Xin, Qian Huang, Jian-Qin Tang, Xiao-Yang Hou, Pei Zhang, Long Zhen Zhang, Guan Jiang
https://pubs.acs.org/doi/abs/10.1021/acs.nanolett.8b04236
Delivery of therapeutics into the solid tumor microenvironment is a major challenge for cancer nanomedicine. Administration of certain exogenous enzymes which deplete tumor stromal components has been proposed as a method to improve drug delivery. Here we present a protein-free collagen depletion strategy for drug delivery into solid tumors, based on activating endogenous matrix ...Author: Xiao Dong, Hai-Jun Liu, Hai-Yi Feng, Si-Cong Yang, Xue-Liang Liu, Xing Lai, Qin Lu, Jonathan F. Love...
https://pubs.acs.org/doi/10.1021/ma401529w
Nov 27, 2013 · This Perspective highlights recent work in integrating liposomes and stimuli-responsive polymers together to achieve a targetable, triggerable nanoscale platform that fulfills all the characteristics of a near-ideal drug delivery system. Through a drop-in, post-synthesis modification strategy, a network of stimuli-responsive polymers can be...Author: Sang Min Lee, Sang Min Lee, Sonbinh T. Nguyen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926460/
As a consequence, CNS disorders, including degenerative diseases, can occur independently of an individual’s age. Although the BBB is crucial in regulating the biochemical environment that is essential for maintaining neuronal integrity, it limits drug delivery to the CNS.Author: Renad Alyautdin, Igor Khalin, Mohd Ismail Nafeeza, Muhammad Huzaimi Haron, Dmitry Kuznetsov
https://pubs.rsc.org/en/content/articlelanding/2017/nr/c6nr08486a
Important considerations for the rational design of PLN for advanced nanoscale drug delivery are discussed, including selection of excipients, synthesis processes governing formulation parameters, optimization of nanoparticle properties, improvement of particle surface functionality to overcome macroscopic, microscopic and cellular biological barriers.Author: Rui Xue Zhang, Taksim Ahmed, Lily Yi Li, Jason Li, Azhar Z. Abbasi, Xiao Yu Wu
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