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https://www.ncbi.nlm.nih.gov/pubmed/19415467
Nanoparticulate delivery systems, with their potential to control drug release profiles, prolonging the presence of drugs in circulation, and to target drugs to a specific site, hold tremendous promise as delivery strategies for therapeutics. Growth factors are endogenous polypeptides that initiate intracellular signals to regulate cellular activities, such as proliferation, migration and differentiation.Author: Sufeng Zhang, Hasan Uludağ
https://link.springer.com/article/10.1007/s11095-009-9897-z
May 05, 2009 · However, the outcome of growth factor therapeutics largely depends on the mode of their delivery due to their rapid degradation in vivo, and non-specific distribution after systemic administration. In order to overcome these impediments, nanoparticulate delivery systems are being harnessed for spatiotemporal controlled delivery of growth factors.Author: Sufeng Zhang, Hasan Uludağ
https://www.researchgate.net/publication/24401737_Nanoparticulate_Systems_for_Growth_Factor_Delivery
nanoparticulate systems designed for effective intact growth factor delivery. The therapeutic applications The therapeutic applications of growth factors delivered by such systems are reviewed ...
https://www.deepdyve.com/lp/springer-journals/nanoparticulate-systems-for-growth-factor-delivery-UzlU0xoNbx
May 05, 2009 · Nanoparticulate Systems for Growth Factor Delivery Nanoparticulate delivery systems, with their potential to control drug release profiles, prolonging the presence of drugs in circulation, and to target drugs to a specific site, hold tremendous promise as delivery …
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/nanoparticle
Neurotrophic factors are neuroprotective in function, thus playing a vital role in reversing AD symptoms. 67 However, a few impediments such as plasma clearance within a short time period and enzymatic degradation were found to curb their success. 68,69 To overcome these issues, a few invasive and expensive strategies were employed such as convention-enhanced delivery and intrathecal and …
https://www.nature.com/articles/nrd4333
Oct 07, 2014 · Nanoparticulate pharmaceutical drug delivery systems (NDDSs) are used in research and clinical settings to overcome several issues associated with traditional drugs, such as poor aqueous solubility, low bioavailability and nonspecific distribution in the body, and to enhance drug efficiency.Author: Vladimir P. Torchilin, Vladimir P. Torchilin
https://www.sciencedirect.com/science/article/pii/S0168365916309671
This article aims to fill this gap by presenting a synopsis of the latest development of hydrogel-based nanoparticulate systems as drug carriers, with a special focus on the in vivo context. It is hoped that with existing advances as the foundation, directions for future research can be illuminated to enhance the clinical potential of hydrogel-based nanoparticulate systems in treatment development and drug …Author: Wing-Fu Lai, Wing-Fu Lai, Zhen-Dan He
https://www.nature.com/articles/am2017171
Oct 06, 2017 · Growth factors (GFs) as powerful therapeutic agents for tissue regeneration. GFs are soluble proteins secreted by cells that have the ability to regulate a wide range of cellular behaviors, such as proliferation, migration and differentiation, by binding to …Author: Zhenming Wang, Zhefeng Wang, William Weijia Lu, Wanxin Zhen, Dazhi Yang, Songlin Peng
https://www.researchgate.net/publication/234071146_A_nanoparticulate_injectable_hydrogel_as_a_tissue_engineering_scaffold_for_multiple_growth_factor_delivery_for_bone_regeneration
A nanoparticulate injectable hydrogel as a tissue engineering scaffold for multiple growth factor delivery for bone regeneration.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053196/
In this context, micro- and nanostructured systems have been used as delivery platforms, 19,20 and are a promising formulation strategy for the therapeutic use of growth factors …Author: Juliana de Souza Rebouças, Nereide Stela Santos-Magalhães, Fabio Rocha Formiga, Fabio Rocha Formiga
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