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https://www.ncbi.nlm.nih.gov/pubmed/18190833/
Nanoparticles (size in nanometer range) provide a new mode of cancer drug delivery functioning as a carrier for entry through fenestrations in tumor vasculature allowing direct cell access. These particles allow exquisite modification for binding to cancer cell membranes, the microenvironment, or to cytoplasmic or nuclear receptor sites.Author: Barbara Haley, Eugene Frenkel
https://www.sciencedirect.com/science/article/pii/S0165247817301761
In a traditional oral or intravascular drug delivery approaches, therapeutic factors are distributed throughout the body and only a small part of the drug reaches to tumor site. Tumor specific targeted drug delivery leads to accumulation of drug in the tumor region …Author: Behdokht Bahrami, Behdokht Bahrami, Mohammad Hojjat-Farsangi, Mohammad Hojjat-Farsangi, Hamed Mohamm...
https://www.sciencedirect.com/science/article/pii/S0142961213012647
The autophagosomes sequester the endo-lysosome escaped NPs into the double membrane vesicles and transport them to lysosomes for degradation, which hinders the advantages of nanoparticles applied for intracellular drug delivery. Moreover, cancer cells depend on autophagy to resist the chemotherapeutics drugs for survival.Author: Xudong Zhang, Yichen Dong, Xiaowei Zeng, Xin Liang, Xiaoming Li, Wei Tao, Hongbo Chen, Yuyang Jiang,...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649002/
Aug 28, 2017 · Furthermore, 2-amino-2-deoxy-glucose was conjugated to -COOH-modified cobalt ferrite MNPs, which were designed to target tumor cells as a potential targetable drug/gene delivery agent for cancer treatment . In summary, MNPs may provide a high-efficiency drug delivery system with the potential to achieve drug targeting.Author: Meijia Wu, Shengwu Huang
https://www.researchgate.net/publication/5660372_Nanoparticles_for_Drug_Delivery_in_Cancer_Treatment
Nanoparticles (size in nanometer range) provide a new mode of cancer drug delivery functioning as a carrier for entry through fenestrations in tumor vasculature allowing direct cell access.
https://www.nature.com/articles/s41392-017-0004-3
Mar 16, 2018 · Nanocarriers for drug delivery. Nanomedicine is a rapidly developing area that is revolutionizing cancer diagnosis and therapy. Nanoparticles …Author: Sudipta Senapati, Arun Kumar Mahanta, Sunil Kumar, Pralay Maiti
https://www.cancer.gov/nano/cancer-nanotechnology/treatment
These properties enable combination drug delivery, multi-modality treatment and combined therapeutic and diagnostic, known as “theranostic,” action. The physical properties of nanoparticles, such as energy absorption and re-radiation, can also be used to disrupt diseased tissue, as in laser ablation and hyperthermia applications.
https://www.hindawi.com/journals/bmri/2014/895986/
In this review, we discuss the recent advances in the use of different types of nanoparticles for systemic and topical drug delivery in the treatment of skin cancer. In particular, the progress in the treatment with nanocarriers of basal cell carcinoma, squamous cell carcinoma, and melanoma has been reported.Author: Chiara Dianzani, Gian Paolo Zara, Giovanni Maina, Piergiorgio Pettazzoni, Stefania Pizzimenti, Feder...
https://www.cancer.gov/nano/cancer-nanotechnology/benefits
This image shows magnetic iron nanoparticles that target cells with IGF-1R receptors, and are conjugated to a chemotherapy drug (dark blue). In the tumor stroma of a mouse model of pancreatic cancer, the nanoparticles delivered the chemotherapy to tumor-associated macrophages expressing IGF-1R (red) and CD68 (green).
https://www.youtube.com/watch?v=RBjWwlnq3cA
Jan 15, 2010 · A short animation outlining the fundamentals of targeted nanomedicine for cancer therapy, one of our group's primary research focuses. For more information, ...Author: FGRGAnimation
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