Nanoparticle Drug Delivery System For Restenosis

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Nanoparticle drug delivery system for restenosis ...

    https://www.sciencedirect.com/science/article/abs/pii/S0169409X96004838
    In this review we discuss the therapeutic potential of nanoparticles as a drug delivery system for restenosis. Nanoparticles, for the purpose of this review, are 30–500 nm diameter polymeric spherical particles. Nanoparticles possess several advantages as a carrier system for the intra-arterial localization of therapeutic agents.Author: Vinod D Labhasetwar, Cunxian Song, Robert J. Levy

Nanoparticle drug delivery system for restenosis ...

    https://www.sciencedirect.com/science/article/pii/S0169409X96004838
    Advantages of nanoparticles as a drug carrier in restenosis Nanoparticles, composed of polymeric material with an entrapped therapeutic agent attached or adsorbed, possess several properties as a drug deliv- ery system which are advantageous for intra-arterial localization of therapeutic agent(s).Author: Vinod D Labhasetwar, Cunxian Song, Robert J. Levy

Nanoparticle-based targeted drug delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249419/
    For example, localized delivery of drug-bearing nanoparticles to sites of vascular restenosis may be useful for providing sustained drug release at specific sites on …Author: Rajesh Singh, James W. Lillard, James W. Lillard

Restenosis Treatments Using Nanoparticle-based Drug ...

    http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1381-6128&volume=19&issue=35&spage=6330
    Keywords:Restenosis, nanoparticle, drug delivery, layered double hydroxide. Abstract:Restenosis, the re-narrowing of a blood vessel after removal of atherosclerotic plaque, is a major limitation of surgical treatments for atherosclerosis. Various attempts to prevent or treat restenosis by pharmacological or mechanical approaches have had limited success in clinical trials.

Nanoparticle Drug- and Gene-eluting Stents for the ...

    https://www.thno.org/v04p0175.htm
    Of the drugs investigated for restenosis prevention and treatment, only paclitaxel and sirolimus have been successfully administered through nanoparticle-based delivery systems and only in …

Nanotechnology for the treatment of coronary in stent ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102631/
    A nanoparticle based approach is ideal for the treatment of restenosis since targeted delivery of nanoparticles is feasible and much lower concentrations of the active drug …Author: Garry McDowell, Mark Slevin, Mark Slevin, Jerzy Krupinski

Drug delivery and nanoparticles: Applications and hazards

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
    The aims for nanoparticle entrapment of drugs are either enhanced delivery to, or uptake by, target cells and/or a reduction in the toxicity of the free drug to non-target organs. Both situations will result in an increase of therapeutic index, the margin between the doses resulting in a therapeutic efficacy (eg,...Author: Wim H De Jong, Paul Ja Borm

Nanotechnology-based drug delivery systems: Challenges and ...

    https://www.sciencedirect.com/science/article/pii/B9780128136898000021
    Nanoparticle drug delivery systems (NPDDS) achieve superior entry for the particles inside the body, as their size permits conveyance by means of intravenous infusion or different courses. Another important use of the NPDDS is in the production of the antibodies …Author: Deepti Sharma, Navneet Sharma, Mallika Pathak, Paban K. Agrawala, Mitra Basu, Himanshu Ojha

Nanoparticle drug delivery system for restenosis, Advanced ...

    https://www.deepdyve.com/lp/elsevier/nanoparticle-drug-delivery-system-for-restenosis-IOytO3iN2q
    In recent years, several local drug delivery strategies have been investigated for the prevention of restenosis. In this review we discuss the therapeutic potential of nanoparticles as a drug delivery system for restenosis. Nanoparticles, for the purpose of this review, are 30–500 nm diameter polymeric spherical particles.

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