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https://www.ncbi.nlm.nih.gov/pubmed/23837855
Nanomedicine strategies for drug delivery to the ear. Pritz CO(1), Dudás J, Rask-Andersen H, Schrott-Fischer A, Glueckert R. Author information: (1)Department of Otolaryngology, Medical University of Innsbruck, Innsbruck, Anichstraße 35, Austria.Author: Christian Oliver Pritz, József Dudás, Helge Rask-Andersen, Anneliese Schrott-Fischer, Rudolf Gluecke...
https://www.researchgate.net/publication/248383186_Nanomedicine_strategies_for_drug_delivery_to_the_ear
Modern strategies do not only enhance drug delivery efficiency, in the inner ear these vector systems also aim for specific uptake into hair cells and spiral ganglion neurons.
http://www.diva-portal.org/smash/record.jsf?pid=diva2:644530
In this article, we summarize the nanotechnology-based efforts involving nano-objects, such as liposomes, polymersomes, lipidic nanocapsules and poly( lactic-co-glycolic acid) nanoparticles, as well as nanocoatings of implants to provide an efficient means for drug transfer in the ear. Modern strategies do not only enhance drug delivery efficiency, in the inner ear these vector systems also aim …
https://www.ncbi.nlm.nih.gov/pubmed/22106854
The methods currently available for inner ear drug delivery are limited and a noninvasive cell-specific drug delivery strategy needs to be found.AIM: In this study we investigated the ability of polymersomes, lipid core nanocapsules and hyperbranched poly-L-lysine to cross the round window membrane.Author: Soumen Roy, Rudolf Glueckert, Alex H Johnston, Thomas Perrier, Mario Bitsche, Tracey A Newman, Patri...
https://eprints.soton.ac.uk/198761/
Jan 01, 2012 · Hearing loss is a very significant health problem. The methods currently available for inner ear drug delivery are limited and a noninvasive cell-specific drug delivery strategy needs to be found. Aim: in this study we investigated the ability of polymersomes, lipid core nanocapsules and hyperbranched poly-L-lysine to cross the round window membrane. <br/><br/>Materials & …Author: Soumen Roy, Rudolf Glueckert, Alex H Johnston, Thomas Perrier, Mario Bitsche, Tracey A Newman, Patri...
https://www.sciencedirect.com/science/article/pii/S1773224717300266
Local drug delivery based on nanoparticles (NP) represents a novel strategy to improve inner ear treatments. The intratympanic delivery of NP may be suitable to treat or prevent hearing loss originating from damage to hair cells and spiral ganglion neurons in the cochlea.Author: Filippo Valente, Laura Astolfi, Edi Simoni, Serena Danti, Valeria Franceschini, Milvia Chicca, Aless...
http://cdn.intechopen.com/pdfs/21213/InTech-Nanomedicine_and_drug_delivery_strategies_for_treatment_of_genetic_diseases.pdf
Nanomedicine and Drug Delivery Strategies for Treatment of Genetic Diseases 247 Fig. 3. Passive (A) and active (B) targeting of drug carriers helps localize their cargo within the body, either via non-specific interactions with the target cells (i) or more specific recognition of particular surface markers (ii).
https://www.futuremedicine.com/toc/nnm/8/7
Nanomedicine welcomes unsolicited article proposals. ... Time-regulated drug delivery system based on coaxially incorporated platelet α-granules for biomedical use. ... Nanomedicine strategies for drug delivery to the ear. Christian Oliver Pritz, József Dudás, Helge Rask-Andersen,
https://www.nanowerk.com/spotlight/spotid=51090.php
Sep 18, 2018 · Nanoclew or nanococoon is a DNA based biocompatible drug delivery system. In this system single stranded DNA makes whole nanococoon. It self assembles to look like a yarn or cocoon or a clew like structure by rolling-circle amplification.
https://www.sciencedirect.com/science/article/pii/S2211383513000178
Intratympanic delivery to the inner ear was performed via the injection or perfusion of the drug to the middle ear with the aim of drug diffusion through the RWM into the inner ear. This route of drug delivery was introduced more than half a century ago for the treatment of Meniere's disease with local anesthetics 50 and antibiotics 51 , 52 and has been widely used in clinics since 1990s.Author: Hongzhuo Liu, Hongzhuo Liu, Jinsong Hao, Kevin S. Li
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