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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2837941/
Systemic delivery of oligonucleotides (ODN) to the central nervous system is needed for development of therapeutic and diagnostic modalities for treatment of neurodegenerative disorders. Macromolecules injected in blood are poorly transported across the blood–brain …
https://pubs.acs.org/doi/10.1021/bc034164r
Systemic delivery of oligonucleotides (ODN) to the central nervous system is needed for development of therapeutic and diagnostic modalities for treatment of neurodegenerative disorders. Macromolecules injected in blood are poorly transported across the blood−brain barrier (BBB) and rapidly cleared from circulation. In this work we propose a novel system for ODN delivery to the brain based ...Author: Serguei V. Vinogradov, Elena V. Batrakova, Alexander V. Kabanov
https://www.researchgate.net/publication/8910571_Nanogels_for_Oligonucleotide_Delivery_to_the_Brain
Nanogel particles made up of PEG and polyethylenimine (>100 nm) have been exploited to cross the BBB for delivery of oligonucleotides to the brain [77]. Also, nanogels are employed for pH ...
https://www.ncbi.nlm.nih.gov/pubmed/14733583
Nanogels for oligonucleotide delivery to the brain. Vinogradov SV(1), Batrakova EV, Kabanov AV. Author information: (1)College of Pharmacy, Department of Pharmaceutical Sciences, University of Nebraska Medical Center, 986025 Nebraska Medical Center, Omaha, Nebraska 68198-6025, USA.Author: Serguei V. Vinogradov, Elena V. Batrakova, Alexander V. Kabanov
https://nebraska.pure.elsevier.com/en/publications/nanogels-for-oligonucleotide-delivery-to-the-brain
Jan 01, 2004 · title = "Nanogels for Oligonucleotide Delivery to the Brain", abstract = "Systemic delivery of oligonucleotides (ODN) to the central nervous system is needed for development of therapeutic and diagnostic modalities for treatment of neurodegenerative disorders.Author: Serguei V. Vinogradov, Elena V. Batrakova, Alexander V. Kabanov
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/nanogel
In the targeted drug delivery system, nanogels can be used widely due to having versatile properties. They exhibit stimuli response behavior, swelling and softness, as well as site specificity [26]. They can be used for delivery of protein therapeutics [30], for combination drug delivery [31], and for oligonucleotide delivery [32]. Thus ...
https://www.imedpub.com/articles/nanogels-as-novel-drug-delivery-systems--a-review.php?aid=18950
Mar 23, 2017 · Vinogradov SV1, Batrakova EV, Kabanov AV (2004)Nanogels for Oligonucleotide Delivery to the Brain.BioconjugChem15:50–60. Shah PP, Desai PR, Patel AR, Singh M (2012) Skin permeating nanogel for the cutaneous co-delivery of two anti-inflammatory drugs.Biomaterials 33: 1607–1617.Author: Hemant Ks Yadav, Noor Anwar Al Halabi, Ghufran Ayman Alsalloum
http://www.sciepub.com/reference/189185
Nanogels are one of the techniques in nanotechnology which has been most prevalent in successful medication delivery inside the body and in addition topical treatment. The nanoparticulate frameworks are materials having under 100 nm in any event in one measurement.
https://www.sciencedirect.com/science/article/pii/S1359644617305767
Trends in nanogel-based drug delivery to the CNS. To highlight the emergence of nanogels in the field of CNS delivery, we focus on studies using hydrogels for the treatment of brain tumors and for tissue engineering, which render them ideal candidates for CNS delivery.Author: Arti Vashist, Ajeet Kaushik, Atul Vashist, Jyoti Bala, Roozbeh Nikkhah-Moshaie, Vidya Sagar, Madhava...
https://www.nature.com/articles/nrd.2015.21
Jan 22, 2016 · Research on the blood–brain barrier (BBB) has led to the concept of a complex, dynamic interface between the central nervous system (CNS) and periphery. Banks considers how this new ...Author: William A. Banks
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