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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626933/
A consequent step was to move from micronization to nanonization. Since the beginning of the 90s, Elan Nanosystems (San Francisco, CA, USA) propagated the use of nanocrystals instead of microcrystals for oral bioavailability enhancement, but also to use nanocrystals suspended in water (nanosuspensions) for intravenous or pulmonary drug delivery.Author: Jens-Uwe A H Junghanns, Rainer H Müller
https://pdfs.semanticscholar.org/b2a2/2c584acb2c980b608d2d415a50f285481b26.pdf
characteristics of drug nanocrystals, and to develop feasible nanocrystal applications for ocular and oral drug delivery purposes. Hence, develop-ability issues from the analytical difficulties of the drug dissolution behavior to the scale-ability of the nanocrystals were covered. A new approach in dissolution testing of nanocrystals,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788714/
Nanocrystals are pure drug crystals with sizes in the nanometer range. Due to the advantages of high drug loading, platform stability, and ease of scaling-up, nanocrystals have been widely used to deliver poorly water-soluble drugs.Author: Yi Lu, Ye Li, Wei Wu
https://www.future-science.com/doi/10.4155/tde-2020-0016
Mar 11, 2020 · Nanocrystals are used as a drug-delivery platform for poorly water-soluble drugs and have had commercial success in oral drug delivery. We assert that the future of this technique is with cancer treatment and in the development of parenteral preparations.Author: Zhongjian Chen, Wei Wu, Wei Wu, Yi Lu, Yi Lu
https://www.entegris.com/content/en/home/resources/reference-materials/application-notes/appnote-drug-delivery-using-nanoparticles-10549.html
DRUG DELIVERY USING NANOPARTICLES Considerable research and development is devoted to improving drug delivery through the use of nanoparticles.
https://www.sciencedirect.com/science/article/pii/S2211383515300319
Nanocrystals are pure drug crystals with sizes in the nanometer range. Due to the advantages of high drug loading, platform stability, and ease of scaling-up, nanocrystals have been widely used to deliver poorly water-soluble drugs.Author: Yi Lu, Ye Li, Wei Wu
https://www.sciencedirect.com/science/article/pii/S0169409X19300699
Nanocrystal formulation enables delivery of poorly soluble drugs and offers key advantages over conventional techniques . In addition to oral and intravenous delivery, nanocrystal formulations have shown great potentials in drug delivery via transdermal, ocular, and pulmonary routes [10,, , , ,149].Author: Yi Lu, Yi Lu, Yongjiu Lv, Tonglei Li
https://www.researchgate.net/publication/275226328_Nanocrystal_technology_for_drug_formulation_and_delivery
Tzu-Lan CHANG et al. Nanocrystal technology for drug formulation and delivery 9 drug; relevant theoretical supports are the Kelvin [64], Ostwald-Freundlich, and Prandtl equations [17].
https://www.researchgate.net/publication/272565469_A_REVIEW_ON_SIGNIFICANCE_OF_NANOCRYSTALS_IN_DRUG_DELIVERY
Nanocrystal is a new carrier free colloidal drug delivery system with particle size ranging from 100-1000 nm, and is considered as a viable drug delivery strategy to develop the poorly soluble drugs. In the present work an attempt was made to enhance bioavailability of Griseofulvin by nanocrystallization …
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