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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2526354/
Nanocarriers as pulmonary drug delivery systems to treat and to diagnose respiratory and non respiratory diseases Malgorzata Smola , 1, 2 Thierry Vandamme , 1 and Adam Sokolowski 2 1 Université Louis Pasteur, Faculté de Pharmacie, Département de Chimie Bioorganique, Illkirch Graffenstaden, FranceAuthor: Malgorzata Smola, Thierry Vandamme, Adam Sokolowski
https://www.sciencedirect.com/science/article/pii/S1773224719317137
Pulmonary drug delivery is attempted for treatment of diseases like tuberculosis , cancer , bacterial infections [48,49]. When compared with intravenous route, delivery and action of hormones, insulin and other proteins by inhalation route is more efficacious . There are three possible mechanisms of particle transport in lung, impaction, sedimentation and diffusion.Author: Monica Joshi, Mangal Nagarsenkar, Bala Prabhakar
https://academic.oup.com/jac/article/70/11/2945/2363606
Jul 22, 2015 · Drug delivery by means of DPIs is considered the most convenient, as it is free of propellant and is chemically stable and patient friendly. Usually, however, drug or nanocarriers have to undergo additional formulation steps in order to be suitable for DPI administration. 23Author: M. Moreno-Sastre, M. Moreno-Sastre, M. Pastor, M. Pastor, C. J. Salomon, C. J. Salomon, A. Esquisabe...
https://www.researchgate.net/publication/5362929_Nanocarriers_as_pulmonary_drug_delivery_systems_to_treat_and_to_diagnose_respiratory_and_non_respiratory_diseases
Nanocarriers as pulmonary drug delivery systems Diffusional deposition occurs mostly when the particles have just entered the nasopharynx, and is also most likely to occur
https://www.sciencedirect.com/science/article/abs/pii/S1773224719317137
Albumin, abundantly present in human body, is a biocompatible and biodegradable polymer used in drug delivery systems. It is relatively an inexpensive polymer with several advantages like non-toxicity, high drug loading capacity, binding efficiency with many drugs which qualifies it as an ideal nanocarrier.Author: Monica Joshi, Mangal Nagarsenkar, Bala Prabhakar
http://www.eurekaselect.com/121255/article
Pulmonary delivery of locally-acting drugs encapsulated in nanocarriers provides several advantages for the treatment of respiratory diseases such as asthma, chronic obstructive pulmonary diseases, cystic fibrosis, tuberculosis and lung cancer.
https://www.researchgate.net/publication/5324598_Biodegradable_polymeric_nanocarriers_for_pulmonary_drug_delivery
Pulmonary drug delivery is attractive for both local and systemic drug delivery as a non-invasive route that provides a large surface area, thin epithelial barrier, high blood flow and the ...
https://www.nature.com/articles/s41467-018-05079-7
Jul 11, 2018 · Drug delivery by nanocarriers (NCs) has long been stymied by dominant liver uptake and limited target organ deposition, even when NCs are targeted using affinity moieties.Author: Jacob S. Brenner, Daniel C. Pan, Jacob W. Myerson, Oscar A. Marcos-Contreras, Carlos H. Villa, Priya...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013600/
Apr 08, 2014 · Pulmonary drug delivery is rapidly gaining importance, due to the multiple advantages. Lungs offer a vast variety of advantages over conventional oral drug delivery. The large surface area and the elimination of the first past effect makes the absorption of drugs in the lungs faster.Author: Mukta Paranjpe, Christel C. Müller-Goymann
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