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https://www.sciencedirect.com/science/article/pii/S0168365918305935
Therefore, such a delivery vehicle offers interesting opportunities for a rational design intended to further enhance the already shown potential for oral peptide delivery. From our perspective, another type of NCs of potential interest for oral peptide delivery is the one making use of the cationic polypeptide, protamine.Author: Lungile Nomcebo Thwala, Lungile Nomcebo Thwala, Diego Pan Delgado, Kevin Leone, Ilaria Marigo, Feder...
https://www.ncbi.nlm.nih.gov/pubmed/30343137
Dec 10, 2018 · A key limitation of these active molecules relies on the difficulties for their efficient oral administration. The objective of this work has been the rational design of polymer nanocapsules (NCs) intended for the oral delivery of peptide drugs. For this purpose, we selected insulin glulisine as a …Author: Lungile Nomcebo Thwala, Lungile Nomcebo Thwala, Diego Pan Delgado, Kevin Leone, Ilaria Marigo, Feder...
https://www.sciencedirect.com/science/article/pii/016836599090013J
Nanocapsules composed of biodegradable spherical polymeric vesicles, less than 300 nm in diameter, were applied for the oral administration of peptides, especially insulin. Nanocapsules were formed by interfacial polymerisation of isobutyl 2-cyanoacrylate around a …Author: C. Damgé, C. Michel, M. Aprahamian, P. Couvreur, J.P. Devissaguet
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648923/
Apr 05, 2012 · Nanocapsules for oral delivery of peptides and proteins. Nanocapsules are used as carriers for oral administration of peptides and proteins, particularly biodegradable poly (isobutylcyanoacrylate) nanocapsules (Puglisi et al 1995, Hildebrand et al 2000). ... Couvreur P and Devissaguet JP . 1990 Nanocapsules as carriers for oral peptide delivery ...Author: Pavankumar Kothamasu, Hemanth Kanumur, Niranjan Ravur, Chiranjeevi Maddu, Radhika Parasuramrajam, Si...
https://www.researchgate.net/publication/328377439_Protamine_nanocapsules_as_carriers_for_oral_peptide_delivery
Protamine nanocapsules as carriers for oral peptide delivery Article in Journal of Controlled Release 291 · October 2018 with 48 Reads How we measure 'reads'
https://www.researchgate.net/publication/310388550_Polyarginine_Nanocapsules_as_a_Potential_Oral_Peptide_Delivery_Carrier
Request PDF Polyarginine Nanocapsules as a Potential Oral Peptide Delivery Carrier We have previously reported the development of novel nanocapsules made of polyarginine (PArg) specifically ...
https://www.ingentaconnect.com/content/asp/jnn/2006/00000006/f0020009/art00032
We have recently reported preliminary data showing the efficacy of chitosan nanocapsules as carriers for oral peptide delivery. In the present work, our aim was to investigate the influence of some chitosan properties, such as the molecular weight and type of salt, on the interaction of these nanocapsules with the Caco-2 cells and also on their in vivo effectiveness.
https://core.ac.uk/display/78462468
Protamine nanocapsules as carriers for oral peptide delivery . By Lungile Nomcebo Thwala. Abstract. The use of nanotechnologies to develop nanocarriers for oral insulin delivery is one of the strategies that has received significant attention. The basis for this development has been that nanocarriers can protect the peptides against the harsh ...Author: Lungile Nomcebo Thwala
https://www.academia.edu/8565750/Chitosan_PEG_nanocapsules_as_new_carriers_for_oral_peptide_delivery
Chitosan–PEG nanocapsules as new carriers for oral peptide delivery
https://link.springer.com/article/10.1007/s11095-006-9570-8
Mar 16, 2006 · We have previously shown that high molecular weight (MW > 100 kDa) chitosan nanocapsules are efficient vehicles for improving the oral absorption of salmon calcitonin (sCT). In the present work, our objectives were, first, to investigate the influence of some formulation parameters on the efficacy of chitosan nanocapsules as carriers for the oral administration of sCT and, second, to …Author: C. Prego, M. Fabre, D. Torres, M. J. Alonso
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