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https://www.sciencedirect.com/science/article/pii/S092151071100496X
Nano-sized calcium phosphate (CaP) carriers for non-viral gene deilvery. ... Schematics of pDNA-Calcium phosphate gene delivery. Once the pDNA-CaP complex is formed by the coprecipitation process, the complex enters the cell through endocytosis. ... NanoCaPs is a term applied for the nano sized HA phase indicated above following the ...Author: Donghyun Lee, Kalpesh Upadhye, Prashant N. Kumta
https://www.sciencedirect.com/science/article/abs/pii/S092151071100496X
In this regard, calcium phosphate (CaP) based nano-particles has been considered as one of the candidate non-viral gene delivery vehicles, but has been plagued by inconsistent and low transfection efficiencies limiting its progress. There has been major research effort to improve the consistency and effectiveness of CaP based vectors.
https://www.researchgate.net/publication/251608905_Nano-Sized_Calcium_Phosphate_CaP_Carriers_for_Non-Viral_Gene_Deilvery
Nano-Sized Calcium Phosphate (CaP) Carriers for Non-Viral Gene Deilvery Article in Materials Science and Engineering B 177(3) · February 2012 with 623 Reads How we measure 'reads'
https://onlinelibrary.wiley.com/doi/10.1002/9781118644591.ch6
Nano‐Sized Calcium Phosphate (CaP) Carriers for Non‐Viral Gene/Drug Delivery. Donghyun Lee. ... Modulation of Protection and Release Characteristics of Calcium Phosphate Vector. Calcium Phosphate Carriers for Drug Delivery Systems. Variants of Nano‐Calcium Phosphates: Future Trends of the CaP Delivery Systems.Author: Donghyun Lee, Kalpesh Upadhye, Prashant N. Kumta
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915088/
Jan 15, 2014 · Other critical disadvantages of the calcium phosphate gene transfer system are insufficient efficiency and poor reproducibility compared with other non-viral carriers 44-45. To get rid of these disadvantages, a lot of new methods based on the …Author: Lian Jin, Xin Zeng, Ming Liu, Yan Deng, Nongyue He
http://www.thno.org/v04p0240.htm
Current Progress in Gene Delivery Technology Based on Chemical Methods and Nano-carriers . Lian Jin 1,*, Xin Zeng 2,*, Ming Liu 1, Yan Deng 1,3, Nongyue He 1,3 . 1. State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China 2.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781291/
Sep 11, 2019 · 1. Introduction. Over the past several decades, gene therapy has become one of the most actively developing and promising branches of medicine [1,2,3,4,5].Calcium phosphate (CaP) nanoparticles, as a promising vehicle for gene delivery, have been widely used because of their biocompatibility, biodegradability and adsorptive capacity for nucleic acids [6,7].Author: Ming Zhao, Ji Li, Dawei Chen, Haiyang Hu
https://nsf.gov/awardsearch/showAward?AWD_ID=0933153
Calcium phosphate (CaP) commercial kits have also been known as standard non viral gene delivery vectors although there have been limited studies reported to ascertain their efficacy as non viral gene delivery agents. Nano-sized CaPs called "NanoCaPs" developed by the PI are novel delivery agents for plasmid DNA (pDNA) transfection.
https://www.liebertpub.com/doi/10.1089/cbr.2005.20.141
May 03, 2005 · To explore an efficient gene vector in cancer gene therapy, a novel nonviral vector calcium phosphate nanoparticle (CPNP) was developed. Transmission electromicroscopy and Zeta potential demonstrated that CPNP was 23.5–34.5 nm diameters and had …Author: Ting Liu, Aifa Tang, Guiying Zhang, Yuxiang Chen, Junyi Zhang, Shusong Peng, Zhiming Cai
https://onlinelibrary.wiley.com/doi/full/10.1002/jbm.b.31746
Nanosized hydroxyapatite and other calcium phosphates: Chemistry of formation and application as drug and gene delivery agents ... Nano‐Sized Calcium Phosphate (CaP) Carriers for Non‐Viral Gene/Drug Delivery, Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering, (203-236), (2013). Wiley Online Library. ...Author: Vuk Uskoković, Dragan P. Uskoković
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