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https://www.sciencedirect.com/science/article/pii/S1381514810001835
1. Introduction. Since application of polymeric micelles as nano-scale drug delivery systems (nano-DDS) in the late 1980s , numerous polymer self-assemblies have been extensively developed aimed to deliver various drugs including; low molecular weight anti-cancer drugs, contrast/imaging agents, proteins, plasmid DNA, antisense DNA, and more recently short interfering RNA (siRNA) , , , .Author: Kanjiro Miyata, R. James Christie, Kazunori Kataoka
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Drug delivery and nanoparticles: Applications and hazards. ... and more substances of a chemical nature like various polymers and solid metal containing nanoparticles. It is obvious that the potential interaction with tissues and cells, and the potential toxicity, greatly depends on the actual composition of the nanoparticle formulation ...Author: Wim H De Jong, Paul Ja Borm
https://www.sciencedirect.com/science/article/pii/B9780128140338000175
Drug delivery faces a lot of limitations even with the presence of particles that have tackled many challenges. One of the main issues and concerns in this regard is the cytotoxicity of some polymers involved in the delivery of drug particles, such as peptides, proteins, and nucleic acid drugs.Author: Hemant K.S. Yadav, Aiah A. Almokdad, Sumia I.M. shaluf, Manar S. Debe
https://pubs.acs.org/doi/10.1021/ja803383k
Redox-Sensitive Nanoscale Coordination Polymers for Drug Delivery and Cancer Theranostics. ACS Applied Materials & Interfaces 2017, 9 (28) , 23555-23563. DOI: 10.1021/acsami.7b07535. Ying Zhang, Yijun Guo, Siyao Wu, Haojun Liang, and Hangxun Xu .Author: William J. Rieter, Kimberly M. Pott, Kathryn M. L. Taylor, Wenbin Lin
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722735/
Aug 20, 2019 · 4. Biodegradable Polymers in Ocular Drug Delivery. Polymers, both synthetic and naturally occurring, have been used for a number of applications in the medical field, including; improved drug delivery, 3-D printing and tissue engineering, attributed to their biocompatible nature.Author: Courtney Lynch, Pierre P. D. Kondiah, Yahya E. Choonara, Lisa C. du Toit, Naseer Ally, Viness Pillay
https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/polymer-nanoparticles-for-smart-drug-delivery
Kidney-targeted drug delivery system can overcome from the various obstacles such as kidney transplantation, ureteral obstruction, diabetes, and other some important kidney disease. Figure 6 shows the kidney drug delivery of nano-particulate systems. Among all drug carriers the macromolecular carriers are extremely powerful targeting the kidney ...Author: Devasier Bennet, Sanghyo Kim
https://file.scirp.org/pdf/JBM_2016011414462012.pdf
of polymers in drug delivery will grow steeply in future to handle various unsolved issues. These issues may in-clude site specific drug delivery in subcellular organelles, harnessing chemical, physical and biological proper-ties efficiently to optimize drug administrations. Nano composites have shown to penetrate deep blood brain barriers [2].
https://www.mdpi.com/journal/polymers/special_issues/drug-delivery
Dear Colleagues, Polymers have performed and will continue to play a central role in drug delivery. These macromolecules are now being used in several drug delivery approaches (e.g., drug and protein conjugates, micro and nanoparticles, nanocapsules, matrices and hydrogels, polymersomes, complexing polymers etc.) or are themselves drugs (e.g., polymers for molecular sequestration).
https://pubs.acs.org/doi/10.1021/acsnano.5b01433
Considerable progress in the synthesis and technology of hydrogels makes these materials attractive structures for designing controlled-release drug delivery systems. In particular, this review highlights the latest advances in nanocomposite hydrogels as drug delivery vehicles. The inclusion/incorporation of nanoparticles in three-dimensional polymeric structures is an innovative means for ...Author: Sonia Merino, Cristina Martín, Kostas Kostarelos, Maurizio Prato, Ester Vázquez
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