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https://www.sciencedirect.com/science/article/pii/S0378517315000083
In conclusion, a multiparticulate pulsatile drug delivery system activated by a rupturable controlled-release membrane via osmotic pressure was successfully developed, and clinical applications of chronotherapy with drugs like propranolol HCl are expected.Author: Sheng Feng Hung, Chien Ming Hsieh, Ying Chen Chen, Cheng Mao Lin, Hsiu O. Ho, Ming Thau Sheu, Ming T...
http://europepmc.org/patents/PAT/WO2008001341
The invention relates to a pharmaceutical composition, comprising at least one micropartide comprising at least one core which is at least partially coated with at least one osmotic subcoat, and at least one outer coat which at least partially coats the at least one osmotic subcoat, wherein said at least one core comprises at least one drug, and at least one excipient, and said at least one osmotic subcoat comprises at least one osmotic agent …
http://europepmc.org/patents/PAT/CA2655596
The invention relates to a pharmaceutical composition, comprising at leas t one micropartide comprising at least one core which is at least partially coated with at least one osmotic subcoat, and at least one outer coat which at least partially coats the at least one osmotic subcoat, wherein said at l east one core comprises at least one drug, and at least one excipient, and s aid at least one osmotic subcoat …
https://ijpras.com/storage/models/article/wcvDGp04NwBZ0OAlbaOx6WMrNeVmOqHtaYpRUPO20bxvtjblJuXPWL5QqwxE/osmotic-drug-delivery-system-an-overview.pdf
1.1.1 Advantage of Osmotic drug delivery system: Os motic drug delivery system for oral use offer distinct and practical advantage over other means of delivery. The following advantages contributed to the popularity of osmotic drug delivery system. 1. They …File Size: 131KB
http://www.bioline.org.br/pdf?pr08028
multiparticulate drug delivery systems are especially suitable for achieving controlled or delayed release. oral formulations with low risk of dose dumping, flexibility of blending to attain different release patterns. as well as reproducible and short gastric residence time.
https://www.slideshare.net/radhipatel05/osmotic-drug-delivery-system
Oct 02, 2013 · Multiparticulate delayed release system 1. In the multiparticulate delayed-release system, pellets containing drug with or without osmotic agent are coated with an SPM-like cellulose acetate. 2. On contact with an aqueous environment, water penetrates into the core and forms a saturated solution of soluble components.
https://www.pharma-iq.com/pre-clinical-discovery-and-development/articles/multiparticulate-drug-delivery-systems
Multiparticulate Drug Delivery Systems. Multiparticulates or multiple unit dosage forms are the discrete, small, repetitive units of drug particles which may or may not possess similar drug release pattern. They can be tailored for pulsatile, controlled and or delayed, targeted drug release depending upon the polymer employed in fabrication.
https://wjpr.net/admin/assets/article_issue/1425551899.pdf
Osmotically Controlled Drug Delivery System (OCDDS) Osmotic devices are the most calculable controlled drug delivery system (CDDS) and can be employed as oral drug delivery systems. Osmotic pressure is used as the driving force for these systems to …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407637/
Jul 17, 2012 · These systems are used for both oral administration and implantation. Osmotic pumps consist of an inner core containing drug and osmogens, coated with a semipermeable membrane. As the core absorbs water, it expands in volume, which pushes the drug solution out through the delivery ports.Author: Rajesh A. Keraliya, Chirag Patel, Pranav Patel, Vipul Keraliya, Tejal G. Soni, Rajnikant C. Patel, M...
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