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https://www.pharma-iq.com/pre-clinical-discovery-and-development/articles/multiparticulate-drug-delivery-systems
Multiparticulate Drug Delivery Systems. Multiparticulates or multiple unit dosage forms are the discrete, small, repetitive units of drug particles which may or may not possess similar drug release pattern. They can be tailored for pulsatile, controlled and or delayed, targeted drug release depending upon the polymer employed in fabrication.
https://www.springer.com/gp/book/9781493970100
Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery.
http://www.bioline.org.br/pdf?pr08028
multiparticulate drug delivery systems are especially suitable for achieving controlled or delayed release. oral formulations with low risk of dose dumping, flexibility of blending to attain different release patterns. as well as reproducible and short gastric residence time.
https://www.slideshare.net/bknanjwade/multiparticulate-drug-delivery-systems
Jan 02, 2015 · Multiparticulate Drug Delivery Systems There are many reasons for formulating a drug as a multiparticulate system for example, to facilitate disintegration in the stomach, or to provide a convenient, fast disintegrating tablet that dissolves in water before swallowing which can aid compliance in older patients and children. Multiparticulate systems show better reproducible pharmacokinetic …
https://link.springer.com/chapter/10.1007/978-1-4939-7012-4_9
May 28, 2017 · Major considerations during paediatric multiparticulate drug development include palatability and taste masking since these are oral dosage forms that release the drug in close proximity of the taste buds, robustness of coatings that give each subunit its individualised functionality, safe use of excipients as well as the ease of extemporaneous preparations where individual dose titration may …Author: Affiong Iyire, Afzal-Ur-Rahman Mohammed
http://www.authorstream.com/Presentation/ravikiranowku-1964647-multiparticulate-drug-delivery-system/
Oct 17, 2013 · Multiparticulate Drug Delivery System - authorSTREAM Presentation. Extrusion–Spheronization : Extrusion–Spheronization Extrusion/Spheronization or maramuerization is a rapid, flexible and a multi step process capable of making uniformly sized spherical particles commonly referred to as spheres or pellets.
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