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https://onlinelibrary.wiley.com/doi/full/10.1002/bit.26566
Combination drug delivery via multilamellar vesicles enables targeting of tumor cells and tumor vasculature. Yarong Liu. Mork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, California. Search for more papers by this author.Author: Yarong Liu, Yu J. Kim, Natnaree Siriwon, Jennifer A. Rohrs, Zhiqiang Yu, Pin Wanga
https://www.sciencedirect.com/science/article/pii/S0169409X1830262X
Liposomes are often considered the archetype of many drug delivery vesicles, originally described half-a-century ago and widely considered the first “nanoscale drug” approved for clinical use [7,8]. Polymersomes are closely related vesicles, assembled from polymers instead of lipids and first reported in the mid-1990s [10,11].Author: Ulrike Kauscher, Margaret N. Holme, Mattias Björnmalm, Molly M. Stevens
https://www.sciencedirect.com/science/article/pii/S0031686599000163
Polymer-coated multilamellar vesicles were prepared as above except for the addition of p-phthaloyl dichloride in the lipid phase.Interfacial polymerization was induced by addition of the aqueous phase (PBS, pH 7.4) containing drug with l-lysine.The monomer ratio, i.e., p-phthaloyl dichloride: l-lysine was kept constant at 0.4:0.4 molar ratio. 2.3.Author: S.P Vyas, N Venkatesan
https://www.nature.com/articles/nmat2960
A potent vaccine-delivery system based on interbilayer-crosslinked multilamellar vesicles is reported. The lipid vesicles enable extracellular co-entrapment of protein antigens and ...Author: James J. Moon, Heikyung Suh, Heikyung Suh, Anna Bershteyn, Matthias T. Stephan, Haipeng Liu, Bonnie ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995748/
However, since their potency is limited by incomplete drug release and inherent instability in the presence of serum components, their poor delivery occurs in certain circumstances. In this study, we address these shortcomings and demonstrate an alternative liposomal formulation, termed …Author: Kye Il Joo, Liang Xiao, Shuanglong Liu, Yarong Liu, Chi Lin Lee, Peter S. Conti, Michael Ka Keu Wong...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077947/
Here we describe a new class of lipid drug carriers, interbilayer-crosslinked multilamellar vesicles (ICMVs), formed by stabilizing multilamellar vesicles with short covalent crosslinks linking lipid headgroups across the opposing faces of adjacent tightly-stacked bilayers within the vesicle walls.Author: James J. Moon, Heikyung Suh, Heikyung Suh, Anna Bershteyn, Matthias T. Stephan, Haipeng Liu, Bonnie ...
https://www.researchgate.net/publication/306418459_VESICULAR_DRUG_DELIVERY_SYSTEM_A_NOVEL_APPROACH
VESICULAR DRUG DELIVERY SYSTEM: A NOVEL APPROACH ... Focus of this review is to bring about a brief of vesicular drug delivery system as novel approach. ... Multilamellar large vesicles- >0.5μm.
https://www.tandfonline.com/doi/pdf/10.3109/10717540903509027
A novel multilamellar vesicular delivery system was developed for the controlled release application. Multilamellar vesicles were prepared by thin film hydration and converted into proliposomes by freeze-drying. A model drug metoclopramide, a highly hydrophilic drug, was successfully encapsulated into pro …
https://www.hindawi.com/journals/ap/2014/574673/
Vesicular drug delivery system can be defined as highly ordered assemblies consisting of one or more concentric bilayers formed as a result of self-assembling of amphiphilic building blocks in presence of water. Vesicular drug delivery systems are particularly important for targeted delivery of drugs because of their ability to localize the activity of drug at the site or organ of action ...Author: Shikha Jain, Vikas Jain, S. C. Mahajan
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