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https://www.nature.com/articles/nrd4333
Oct 07, 2014 · The use of nanoparticulate pharmaceutical drug delivery systems (NDDSs) to enhance the in vivo effectiveness of drugs is now well established. The …Author: Vladimir P. Torchilin, Vladimir P. Torchilin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097927/
Conventional drug delivery systems are useful to some extent in overcoming these issues, but they have failed to prove their effectiveness in delivering many drugs. Nanoparticle assisted drug delivery provides a platform to modify the basic properties of drug molecules viz. solubility, half-life, biocompatibility and its release characteristics.
https://pubs.acs.org/doi/abs/10.1021/mp060076n
This review discusses the development of functional and multifunctional dendrimeric and hyperbranched polymers, collectively called dendritic polymers, with the objective of being applied as drug and gene delivery systems. In particular, using as starting materials known and well-characterized basic dendritic polymers, the review deals with the type of structural modifications to which these ...Author: Constantinos M. Paleos, Dimitris Tsiourvas, Zili Sideratou
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1568-0266&volume=8&issue=14&spage=1204
Keywords:Dendrimers, hyperbranched polymers, dendritic polymers, nanocarriers, drug delivery system, gene delivery. Abstract: This review describes the strategy for the development of multifunctional dendrimeric and hyperbranched polymers, collectively named dendritic polymers, aiming at their application as drug and gene delivery systems ...Author: Constantinos M. Paleos, Dimitris Tsiourvas, Zili Sideratou, Leto Tziveleka
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489143/
The use of nanoparticulate pharmaceutical drug delivery systems (NDDSs) to enhance the in vivo effectiveness of drugs is now well established. The development of multifunctional and stimulus-sensitive NDDSs is an active area of current research.Author: Vladimir P. Torchilin, Vladimir P. Torchilin
https://www.researchgate.net/publication/47808514_Drug_Delivery_Using_Multifunctional_Dendrimers_and_Hyperbranched_Polymers
The review presents the design strategy and synthesis of multifunctional dendrimers and hyperbranched polymers with the objective to develop effective drug delivery systems.
https://www.researchgate.net/publication/254391539_Design_of_functional_dendritic_polymers_for_application_as_drug_and_gene_delivery_systems
Furthermore, having developed these multifunctional liposomal and dendritic carriers, a drug delivery model is presented that employs instead of cells multilamellar liposomes, which interact with ...
https://www.nature.com/articles/s41598-019-39107-3
Feb 25, 2019 · Most targeting strategies of anticancer drug delivery systems (DDSs) rely on the surface functionalization of nanocarriers with specific ligands, which trigger the internalization in cancer cells ...Author: Beatrice Fortuni, Tomoko Inose, Monica Ricci, Yasuhiko Fujita, Indra Van Zundert, Akito Masuhara, Ed...
https://donglab.engineering.osu.edu/research
Research. Cell-specific and multifunctional drug delivery in vivo has been regarded as one of the most challenging issues in the field of drug delivery. A wide variety of cell types in humans still cannot be efficiently and specifically reached by delivery systems such as lung epithelial cells, metastatic tumor cells, and tumor stem cells.
https://www.polymerfactory.com/multifunctional-pegs/
Our hybrid materials consist of linear PEG cores with dendritic wedges attached to the end-groups. These materials present excellent solubility in water and a high number of functionality, making them strong candidates for advanced drug delivery systems or as targeting vessels.
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