We have collected information about Mucosal Drug Delivery Models for you. Follow the links to find out details on Mucosal Drug Delivery Models.
https://www.sciencedirect.com/science/article/abs/pii/S1773224713500554
This review focuses on the impact of the mucus layer on mucosal delivery, reviews the state-of-the-art cell culture in vitro models used, and the formulation strategies applied to improve mucosal drug delivery.Author: M. Boegh, C. Foged, A. Müllertz, H. Mørck Nielsen
https://www.sciencedirect.com/science/article/pii/S1773224713500554
Mucosal drug delivery: barriers, in vitro models and formulation strategies. Delivery of prophylactic and therapeutic drugs via administration to the mucosal sites of …Author: M. Boegh, C. Foged, A. Müllertz, H. Mørck Nielsen
https://www.mattek.com/application/drug-delivery-3/
Drug Delivery (Oral Mucosal) The Model. MatTek’s EpiOral tissues consist of normal, human-derived epithelial cells. The tissues, which are cultured on specially prepared cell culture inserts using serum free medium, attain levels of differentiation on the cutting edge of in vitro cell culture technology.
https://www.researchgate.net/publication/8460157_Mucosal_Drug_Delivery_Membranes_Methodologies_and_Applications
Drug delivery via the oral mucosa can be subdivided into three different approaches: sublingual delivery across the mucosa lining the floor of the mouth, buccal delivery via the mucosa lining the ...
http://dl.begellhouse.com/journals/3667c4ae6e8fd136,16e2a9f911dc5f33,53840f791e19ed7f.html
ABSTRACT. In recent years, extensive research into novel forms of drug delivery has suggested that mucosal approaches offer a promising therapeutic alternative, especially for systemically acting drugs.
http://ijpsr.com/bft-article/a-detailed-review-on-oral-mucosal-drug-delivery-system/?view=fulltext
INTRODUCTION: Oral mucosal drug delivery system is subdivided into buccal and sublingual in which buccal cavity is widely applicable for drug administration through mucosa in case of sublingual route mostly useful for fastest onset of action as in the case of Angina pectoris. The buccal mucosa lines the inner cheek, and buccal formulations are placed in the mouth between the upper gingivae (gums) and …
https://onlinelibrary.wiley.com/doi/full/10.1111/bcpt.12342
Oct 27, 2014 · Other reviews 3, 4 provide a full introduction to drug delivery to all mucosal surfaces including a physiological description of the different mucosal epithelia. The intestinal mucosa is composed of a thin layer of smooth muscle cells (muscularis mucosae), connective tissue (lamina propria) and the epithelium 5. To enter the systemic circulation, a drug compound needs to cross the epithelium and …Author: Marie Boegh, Hanne Mørck Nielsen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513449/
Aug 31, 2012 · Mechanistic Model for Oral Mucosal Absorption Based on Literature. Of the models proposed to study the transport kinetics from the oral cavity into the systemic circulation, the commonality between the majority of the models is an equilibrium term of drug concentration between the oral cavity and the mucosal membranes (3–11). The equilibrium term (or pseudo-equilibrium term owing to the …Author: Jeremy A. Bartlett, Kees van der Voort Maarschalk
https://www.researchgate.net/publication/266050697_A_detail_review_on_oral_mucosa_of_drug_delivery_system
Oral mucosal drug delivery system is widely applicable as novel site for administration of drug for immediate and controlled release action by preventing first pass metabolism and enzymatic degradation due to GI microbial flora. Oral mucosal drug delivery system provides local and systemic action.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513450/
Aug 17, 2012 · Drug release, dissolution in the vaginal discharge, and permeability through the mucosa limit systemic drug delivery or access to locally diseased targets. To identify rate-limiting steps encountered during formulation development, several models have been suggested in pursue for the most optimal one.Author: Katja Berginc, Nataša Škalko-Basnet, Purusotam Basnet, Albin Kristl
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