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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053525/
Ocular Mucoadhesive Drug Delivery Systems. Drug administration to the eye is a challenge because there are several mechanisms (tear production, tear flow, and blinking) that protect the eye from the harmful agents. Conventional delivery methods are not ideal.
https://www.researchgate.net/publication/318159694_Mucoadhesive_Polymers_for_Drug_Delivery_Systems
Mucoadhesive polymers play an important role in the design and development of mucoadhesive drug delivery sys- tems and may be classified on the basis of generation, source, charge, and solubility ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255357/
This update review is on mucoadhesive polymers used in nasal dosage forms. The nasal mucosa provides a potentially good route for systemic drug delivery. One of the most important features of the nasal route is that it avoids first-pass hepatic metabolism, thereby reducing metabolism. The ...
https://www.sciencedirect.com/science/article/pii/S0079670014000859
Mucoadhesive polymers in the design of nano-drug delivery systems for administration by non-parenteral routes: A review ... the benefit of the incorporation of mucoadhesive polymers into the structure of these innovative pharmaceutical products to prolong their residence time in the administration site and the release of the drug cargo will be ...Author: Alejandro Sosnik, José das Neves, Bruno Sarmento
https://www.sciencedirect.com/science/article/pii/S1773224715001112
Mucosa of the buccal cavity is considered a convenient and easily accessible site for the administration of drugs intended for both local and systemic delivery. Aiming to optimize the pharmacokinetic, buccal mucoadhesive drug delivery systems are proposed. Mucoadhesion is a complex process involving chemical interactions between mucin and polymers.Author: Eleonora Russo, F. Selmin, Sara Baldassari, C. G. M. Gennari, Gabriele Caviglioli, F. Cilurzo, P. Mi...
https://www.tandfonline.com/doi/abs/10.1163/138577209X12478283327236
Oct 14, 2004 · Bioadhesion can be defined as the process by which a natural or a synthetic polymer can adhere to a biological substrate. When the biological substrate is a mucosal layer then the phenomena is known as mucoadhesion. The substrate possessing bioadhesive property can help in devising a delivery system capable of delivering a bioactive agent for a prolonged period of time at a specific delivery site.Author: S. Roy, K. Pal, A. Anis, K. Pramanik, B. Prabhakar
https://www.mdpi.com/journal/pharmaceutics/special_issues/mucoadhesive_mucosal_DDS
Moreover, other attempts have been made to optimize mucosal drug delivery, such as mucus-penetrating systems (for reducing mucus interaction), the employment of mucolytic agents (enabling alteration of the mucus structure) and, more recently, self-propagating drug …
http://www.scielo.br/pdf/bjps/v46n1/02.pdf
Drug actions can be improved by developing new drug delivery systems, such as the mucoadhesive system. These systems remain in close contact with the absorption tissue, the mucous membrane, releasing the drug at the action site leading to a bioavailability increase …
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