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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053525/
Mucoadhesive drug delivery systems in the past have been formulated as powders, compacts, sprays, semisolids, or films. For example, compacts have been used for drug delivery to the oral cavity,[ 51 ] and powders and nanoparticles have been used to facilitate drug administration to the nasal mucosa.[ 52 , 53 ] Recently oral strips[ 54 ] were developed for tongue or buccal cavity.
https://www.researchgate.net/publication/221750117_Mucoadhesive_drug_delivery_system_An_overview
Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436075/
Evaluation of Buccal Delivery Systems . Buccal adhesive drug delivery devices are subjected to the routine evaluation tests such as weight variation, thickness variation, friability, hardness, content uniformity, in vitro dissolution for tablets; tensile strength, film endurance, hygroscopicity etc. for films and patches; viscosity, effect of aging etc. for gels and ointments.Author: P Chinna Reddy, Chaitanya K.S.C., Y Madhusudan Rao
http://www.jbr-pub.org.cn/article/doi/10.7555/JBR.27.20120136
A clinical perspective on mucoadhesive buccal drug delivery systems Mucoadhesion can be defined as a state in which two components, of which one is of biological origin, are held together for extended periods of time by the help of interfacial forces.Author: Ritu M Gilhotra, Mohd Ikram, Sunny Srivastava, Neeraj Gilhotra
https://www.sciencedirect.com/science/article/pii/S0939641119303376
Sep 01, 2019 · It was the aim of this study to assess in vitro methods for the characterization of mucoadhesive hydrogels for their potential to predict the residenc…Author: Randi Angela Baus, Forouhe Zahir-Jouzdani, Forouhe Zahir-Jouzdani, Sarah Dünnhaupt, Fatemeh Atyabi, ...
http://www.authorstream.com/Presentation/rosecrx-1830872-mucoadhesive-drug-delivery-system/
May 27, 2013 · Saliva contains proteolytic enzymes which acts as a major enzymatic barrier to the permeation of drug through buccal tissues. The use of mucoadhesive drug delivery system with enzyme inhibitor had been developed to overcome the barrier in the peptide and protein delivery.
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