Molecular Engineering Viral Gene Delivery Vehicles

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Molecular Engineering of Viral Gene Delivery Vehicles

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683887/
    Therefore, engineering viral vectors with new properties, including enhanced targeting abilities and resistance to immune responses, is a growing area of research. This review discusses protein engineering approaches to generate viral vectors with novel gene delivery capabilities.Author: David V. Schaffer, James T. Koerber, Kwang-il Lim

Molecular Engineering of Viral Gene Delivery Vehicles ...

    https://www.annualreviews.org/doi/10.1146/annurev.bioeng.10.061807.160514
    Therefore, engineering viral vectors with new properties, including enhanced targeting abilities and resistance to immune responses, is a growing area of research. This review discusses protein engineering approaches to generate viral vectors with novel gene delivery capabilities.Author: David V. Schaffer, James T. Koerber, Kwang-il Lim

Molecular Engineering of Viral Gene Delivery Vehicles

    https://www.academia.edu/8120551/Molecular_Engineering_of_Viral_Gene_Delivery_Vehicles
    Molecular Engineering of Viral Gene Delivery Vehicles

The next step in gene delivery: molecular engineering of ...

    https://www.ncbi.nlm.nih.gov/pubmed/21029739
    The next step in gene delivery: molecular engineering of adeno-associated virus serotypes. Wang J(1), Faust SM, Rabinowitz JE. Author information: (1)Thomas Jefferson University Center for Translational Medicine, Philadelphia, PA 19107, USA. Delivery is at the heart of gene therapy.Author: Jinhui Wang, Susan M. Faust, Joseph E. Rabinowitz

Gene delivery - Wikipedia

    https://en.wikipedia.org/wiki/Gene_delivery
    Gene delivery is the process of introducing foreign genetic material, such as DNA or RNA, into host cells. Genetic material must reach the nucleus of the host cell to induce gene expression. Successful gene delivery requires the foreign genetic material to remain stable within the host cell and can either integrate into the genome or replicate independently of it.

Cationic polymers for non-viral gene delivery to human T ...

    https://www.sciencedirect.com/science/article/pii/S0168365918301202
    The clinical success of chimeric antigen receptor (CAR) T cell immunotherapy in treating multiple blood cancers has created a need for efficient methods of ex vivo gene delivery to primary human T cells for cell engineering. Here, we synthesize and evaluate a panel of cationic polymers for gene delivery to both cultured and primary human T cells.Author: Brynn R. Olden, Yilong Cheng, Jonathan L. Yu, Suzie H. Pun

Genome engineering: a new approach to gene therapy for ...

    https://www.nature.com/articles/nrneurol.2017.126
    Sep 29, 2017 · Genome engineering tools, including targeted gene editing and gene regulation, are becoming available to correct the mutations that cause neuromuscular disorders such as muscular dystrophy, spinal ...Author: Christopher E. Nelson, Jacqueline N. Robinson-Hamm, Charles A. Gersbach, Charles A. Gersbach

Adenoviruses as Gene-Delivery Vehicles NEJM

    https://www.nejm.org/doi/full/10.1056/NEJM199605023341809
    Molecular Medicine from The New England Journal of Medicine — Adenoviruses as Gene-Delivery Vehicles. ... for Human Gene Therapy and the Department of Molecular and Cellular Engineering ...Author: James M. Wilson

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