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http://pharmaquest.weebly.com/uploads/9/9/4/2/9942916/grdds.pdf
Gastro-retentive delivery is one of the site specific delivery for the delivery of drugs either at stomach or at intestine. It is obtained by retaining dosage form into stomach and drug is being released at controlled manner to specific site either in stomach, duodenum and intestine.
https://innovareacademics.in/journal/ajpcr/Vol3Issue1/250.pdf
Floating drug delivery systems Floating drug delivery systems is one of the important approaches to achieve gastric retention to obtain sufficient drug bioavailability [25]. This delivery systems is desirable for drugs with an absorption window in the stomach or in the upper small intestine [26].
https://ijpras.com/storage/models/article/TeYOGN6dBciE6RSaYCvW8hR2FcFAQVag5S1dwxVGo5yZrYaTt4UG4Qf5nKWQ/gastroretentive-drug-delivery-system-a-review.pdf
systems for drugs with bioavailability problems. The need for Gastroretentive dosage forms (GRDFs) has led to extensive efforts in both academia and industry towards the development of such drug delivery system. Floating drug delivery system has a bulk density lower than gastric fluids
https://www.researchgate.net/publication/235009303_Novel_Drug_Delivery_Systems_for_Modulation_ofGastrointestinal_Transit_Time
Floating drug delivery systems are utilized to target drug release in the stomach or to the upper parts of intestine. Oral delivery of an anti-ulcer agent, famotidine was facilitated by preparing various floating dosage forms which can increase its absorption in the stomach by enhancing gastric residence time.
https://www.pharmatutor.org/articles/overview-on-gastro-retentive-drug-delivery-system
Also prolonged gastric retention time (GRT) in the stomach could be advantageous for local action in the upper part of the small intestine e.g. treatment of peptic ulcer, etc. Gastro retentive drug delivery is an approach to prolong gastric residence time, thereby targeting site-specific drug release in the upper gastrointestinal tract (GIT ...
https://www.slideshare.net/mangasrinivas37/gastro-retentive-drug-delivery-system-advantages-and-approaches
Oct 17, 2012 · gastro retentive drug delivery system Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. If you continue browsing the site, you agree to the use of cookies on this website.
http://www.authorstream.com/Presentation/v.ramani007-1665945-gastro-retentive-drug-delivery-system/
Feb 05, 2013 · ORAL CONTROLLED DRUG DELIVERY SYSTEMS Not applicable to drugs which has any of the following characteristics Narrow absorption window in GI tract E.g. Riboflavin, Levodopa Primarily absorbed from stomach and upper part of GI tract E.g. Calcium supplement, Chlordiazepoxide, Cinnarazine Act locally in stomach E.g. Antacids, Misoprostol Drug that degrade in colon E.g. Ranitidine HCl, Metronidazole Drug …
http://www.authorstream.com/Presentation/johnnybravo8456-1164523-gastro-retentive-drug-delivery-system/
Aug 27, 2011 · DEFINITION These are the drug delivery systems which possess the ability of retaining the drug in the GIT particularly in the stomach for prolonged period of time. After the drug release for required time period the dosage form should get degraded without causing any gastric disturbances.
http://www.thepharmajournal.com/vol1Issue8/Issue_oct_2012/4.1.pdf
fluctuation in plasma drug concentration at steady state by delivering the drug in a controlled and reproducible manner.2 One novel approach in this area is GRDDSs (gastro retentive drug delivery system). Dosage forms that can be retained in the stomach are called GRDDs. GRDDSs can improve the controlled delivery of
http://www.thepharmajournal.com/vol1Issue10/Issue_dec_2012/3.1.pdf
Controlled release drug delivery employs drug-encapsulating devices from which therapeutic agents may be released at controlled rates for long periods of time, ranging from days to months. Such systems offer numerous advantages over traditional methods of drug delivery, including tailoring of drug release rates, protection of fragile
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