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https://pubs.acs.org/doi/pdf/10.1021/ja4117395
Automated Modular Synthesis of Aptamer−Drug Conjugates for Targeted Drug Delivery RuoWen Wang,† Guizhi Zhu,† Lei Mei,† Yan Xie,† Haibin Ma,† Mao Ye,† Feng-Ling Qing,§ and Weihong Tan*,† †Molecular Sciences and Biomedicine Laboratory, State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering and College of Biology, Collaborative ...
https://pubs.rsc.org/en/content/articlelanding/2019/cc/c9cc01391a#!
A multifunctional nanobody–drug conjugate (NDC) was constructed in this work for the targeted delivery of a platinum prodrug and an MRI contrast agent. The NDC can be specifically internalized into EGFR positive cancer cells, resulting in higher therapeutic effect and lower side-effects relative to cisplatin
https://www.scirp.org/journal/PaperInformation.aspx?PaperID=18938
The development of novel drug delivery systems is an essential step toward controlled site-specific administration of therapeutics within the body. It is desirable for delivery vehicles to be introduced into the body through minimally invasive means and, these vehicles should be capable of releasing drug to their intended location at a controlled rate.Author: Susana Simões, Ana Figueiras, Francisco Veiga
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089944/
Apr 20, 2011 · A modular dendrimer-based drug delivery platform was designed to improve upon existing limitations in single dendrimer systems. Using this modular strategy, a biologically active platform containing receptor mediated targeting and fluorescence imaging modules was synthesized by coupling a folic acid (FA) conjugated dendrimer with a fluorescein isothiocyanate (FITC) conjugated dendrimer.Author: Douglas G. Mullen, Daniel Q. McNerny, Ankur Desai, Xue Min Cheng, Stassi C. Dimaggio, Alina Kotlyar,...
https://www.ondrugdelivery.com/a-flexible-modular-platform-to-disrupt-the-blockbuster-manufacturing-model/
Citation: Rollings N, Barker C, Vellacott R, “Early Insight: A Flexible, Modular Platform to Disrupt the Blockbuster Manufacturing Model”. ONdrugDelivery Magazine, Issue 103 (Dec 2019), pp 48-52. Nick Rollings, Colin Barker and Richard Vellacott discuss the drug delivery scenario in …
https://pubs.rsc.org/en/content/articlelanding/2020/nr/c9nr08519j
With the increasing number of identified intracellular drug targets, cytosolic drug delivery has gained much attention. Despite advances in synthetic drug carriers, however, construction of homogeneous and biocompatible nanostructures in a controllable manner still remains a challenge in a translational medi ... Modular protein–DNA hybrid ...Author: Yiseul Ryu, Cheol Am Hong, Yunjin Song, Jonghwi Beak, Bo Am Seo, Joong-jae Lee, Hak-Sung Kim
https://file.scirp.org/pdf/JBNB20120200008_34110999.pdf
186 Modular Hydrogels for Drug Delivery . The present review addresses recent important re- search developments, which have focused in hydrogel systems. Actually, the literature is exhaustive on general aspects about hydrogels. However, the article intends to …
https://techtransfer.universityofcalifornia.edu/NCD/22699.html
Modular Cell and Drug Delivery Cannula System. Tech ID: 22699 / UC Case 2012-063-0. Background. The use of cell transplantation in the brain shows great promise for the treatment of human neurological diseases, such as Parkinson's disease or stroke. Indeed, pre-clinical studies in animal models have shown significantly improved neurological ...
Technology. Shasqi has created a new way to deliver drugs in the body. Our proprietary local drug activation technology allows delivery of more drug to the tumor with fewer side effects.
https://www.researchgate.net/publication/278042305_Modular_drug_delivery_systems_for_personalized_oral_dosage_forms
A drug delivery platform based on a modular dosage forms have been developed at University of Parma (1). Release modules consisted in cylindrical tablets or matrices, having a concave and a convex ...
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