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https://www.sciencedirect.com/science/article/pii/S0928493102002382
The characterization of modified SiO 2 particles by solid-state 29 Si NMR reveals a high condensation degree (>90%) of T-units of the silane modifier. Additional solid-state 29 Si NMR cross-polarization experiments with variable contact time support the assumption that the silane compound is bound to the silica nanoparticles. The absence of epoxide signals in solid-state 13 C NMR spectra ...Author: Zsuzsa Csögör, Manfred Nacken, Mohammad Sameti, Claus-Michael Lehr, Helmut K. Schmidt
https://www.researchgate.net/publication/223740425_Modified_Silica_Particles_for_Gene_Delivery
Modified Silica Particles for Gene Delivery Article in Materials Science and Engineering C 23(1-2):93-97 · January 2003 with 38 Reads How we measure 'reads'
https://www.sciencedirect.com/science/article/abs/pii/S0928493102002382
Modified silica particles for gene delivery. Author links open overlay panel Zs. Csőgör a M Nacken a M Sameti b C.-M Lehr b H Schmidt a. Show more. ... In somatic gene therapy, new concepts for the transfer of DNA into specific cell nuclei are of interest. Inorganic nanoparticles have an interesting potential as DNA carrier system due to the ...Author: Zsuzsa Csögör, Manfred Nacken, Mohammad Sameti, Claus-Michael Lehr, Helmut K. Schmidt
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108588/
The use of MSN in drug/gene delivery requires additional means of steric stabilization due to their strong tendency to aggregate. Surface modification with polycations is known to prevent MSN aggregation, but complexing such particles with DNA or siRNA leads to an increased hydrophobicity and subsequent decrease in colloidal stability.Author: Shanta Raj Bhattarai, Elayaraja Muthuswamy, Amit Wani, Michal Brichacek, Antonio L. Castañeda, Steph...
https://www.pnas.org/content/102/32/11539
Aug 09, 2005 · This article reports on the application of organically modified silica (ORMOSIL) nanoparticles as a nonviral vector for efficient in vivo gene delivery. Highly monodispersed, stable aqueous suspension of nanoparticles, surface-functionalized with amino groups for binding of DNA, were prepared and characterized. Stereotaxic injections of nanoparticles, complexed with plasmid DNA …Author: Dhruba J. Bharali, Ilona Klejbor, Ewa K. Stachowiak, Purnendu Dutta, Indrajit Roy, Navjot Kaur, Earl...
https://www.researchgate.net/profile/Olga_Mykhaylyk/publication/216687059_Silica-Iron_Oxide_Magnetic_Nanoparticles_Modified_for_Gene_Delivery_A_Search_for_Optimum_and_Quantitative_Criteria/links/09e415112cfbe2629e000000.pdf?origin=publication_detail
Mesoporous silica particles have been developed recently ... Fig. 1 Schematics of silica-iron oxide magnetic nanoparticles modified for gene delivery. Magnetic iron oxide nanoparticles with a ...
https://www.nature.com/articles/nnano.2007.108
Apr 29, 2007 · Bharali, D. J. et al. Organically modified silica nanoparticles: A nonviral vector for in vivo gene delivery and expression in the brain. Proc. Natl Acad. Sci. USA 102, 11539–11544 (2005). CAS ...Author: François Torney, Brian G. Trewyn, Victor S.-Y. Lin, Kan Wang
https://link.springer.com/article/10.1007%2Fs11095-011-0661-9
Jan 06, 2012 · To optimize silica-iron oxide magnetic nanoparticles with surface phosphonate groups decorated with 25-kD branched polyethylenimine (PEI) for gene delivery. Surface composition, charge, colloidal stabilities, associations with adenovirus, magneto-tranduction efficiencies, cell internalizations, in vitro toxicities and MRI relaxivities were tested for the particles decorated with varying ...Author: Olga Mykhaylyk, Titus Sobisch, Isabella Almstätter, Yolanda Sanchez-Antequera, Sabine Brandt, Martin...
https://www.cd-bioparticles.com/product/silica-particles-list-168.html
Creative Diagnostics offers a comprehensive list of basic, coated, functional and conjugated silica particles with uniform size and shapes. Our silica particles in the size range of 10 nm to 1.5 µm are monodisperse and nonporous particles with a density of 2.0 g/cm³, while particles between 3 and 20 µm are porous particles with a density of 1.8 g/cm³.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132998/
Aug 01, 2014 · 2.2. Preparation of gold nanoparticle modified silica particles. Spherical unconjugated gold nanoparticles of 15 nm and 30 nm diameter (PGO15 and PGO30, Kisker Biotech, Germany) were used as delivered with a stock concentration of about 0.06 mg/ml. 4 nm gold nanoparticles were prepared by the reduction of gold salt (Gold(III) chloride trihydrate (Sigma, Germany) through sodium …Author: Stefan Kalies, Lara Gentemann, Markus Schomaker, Dag Heinemann, Tammo Ripken, Heiko Meyer
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