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https://www.ijpsonline.com/articles/development-of-modified-pulsincap-drug-delivery-system-of-metronidazole-for-drug-targeting.html
All the formulations were assayed to determine drug content and the ability of the modified Pulsincap to provide colon-specific drug delivery was assessed by in vitro drug release studies in buffer pH 1.2 for 2 h, pH 7.4 (simulated intestinal fluid) for 3 h and pH 6.8 (stimulated colonic fluid) for 7 h.Author: Sindhu Abraham, Srinath
http://www.pharmtech.com/developing-modified-pulsincap-system
Nov 01, 2009 · In our study, a modified Pulsincap device containing DS was developed to target drug release in the colon. This is a sitespecific and timedependent formulation; by administering the formulation at 10.00 pm, symptoms that are experienced early in the morning are avoided.
https://innovareacademics.in/journal/ijpps/Vol6Issue5/7840.pdf
Formulation of pulsatile (modified pulsincap) drug delivery system: Preparation of modified pulsincap Equivalent to 10 mg drug granules were filled in the capsule bodies and plugged with hydrogel plug. The treated body and the cap of the capsules were sealed with a …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465138/
Pulsincap delivery combines advantages of pH-dependent and time-dependent colon targeting and overcomes the disadvantages of conventional method of colonic delivery (pH, time, and microflora-assisted delivery).Modified pulsincap™ dosage form consists of a formaldehyde-treated water-insoluble body and a water-soluble cap.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548250/
Jul 01, 2011 · In other words, they require pulsatile drug delivery system (PDDS). The pulsatile system is gaining a lot of interest, as the drug is released completely after defined lag time (Fig. 1). Pulsatile drug delivery is time and site-specific drug delivery, thus providing spatial and temporal delivery and increasing patient compliance.Author: Deepika Jain, Richa Raturi, Vikas Jain, Praveen Bansal, Ranjit Singh
https://www.researchgate.net/publication/200745129_FORMULATION_AND_EVALUATION_OF_MODIFIED_PULSINCAP_DRUG_DELIVERY_SYSTEM_OF_TRIMETAZIDINE_HYDROCHLRIDE
All the formulations were assayed to determine drug content and the ability of the modified Pulsincap to provide colon-specific drug delivery was assessed by in vitro drug release studies in ...
https://www.ijpsonline.com/articles/development-of-modified-pulsincap-drug-delivery-system-of-metronidazole-for-drug-targeting.pdf
the ability of the modified Pulsincap to provide colon-specific drug delivery was assessed by in vitro drug release studies in buffer pH 1.2 for 2 h, pH 7.4 (simulated intestinal fluid) for 3 h and pH 6.8 (stimulated colonic fluid) for 7 h. The results indicated that significant drug release occurred only after 5 h from the start of experiment.Author: Sindhu Abraham, Srinath
http://www.iosrphr.org/papers/v2i2/ZL022338339.pdf
There is a constant need for new delivery systems that can provide increased therapeutic benefits to the patients. Pulsatile drug delivery is one such system (pulsincap) that, by delivering drug at the right time, right place, and in right amounts, holds
https://quizlet.com/75900300/modified-oral-drug-delivery-systems-v-flash-cards/
Modified Oral Drug Delivery Systems V. ... Time-Dependent Delivery: Pulsincap™ and PORT® Systems. ... The system can be modified to withstand and rupture at different pressures by changing the size of the capsule and thickness of the capsule shell wall. Bacteria-Dependent Delivery.
https://www.researchgate.net/publication/261285184_In-vitro_Characteristics_of_Modified_Pulsincap_formulation_with_Mesalamine
All the formulations were assayed to determine drug content and the ability of the modified Pulsincap to provide colon-specific drug delivery was assessed by in vitro drug release studies in ...
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