Mirus Sirna Delivery

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TransIT-X2 Transfection Reagent - Mirus Bio

    https://www.mirusbio.com/products/transfection/transit-x2-dynamic-delivery-system
    TransIT-X2® Dynamic Delivery System Outperforms Lipofectamine® Reagents. A549 (A) or MDCK (B) cells were transfected with luciferase encoding plasmid DNA using either TransIT-X2® (Mirus Bio), Lipofectamine® 2000 (Thermo Fisher Scientific) or Lipofectamine® 3000 (Thermo Fisher Scientific) for 24 hours at indicated reagent-to-DNA ratios or reagent-to-P3000™-to-DNA ratio.

TransIT® siRNA Transfection Reagents for High Efficiency ...

    https://www.mirusbio.com/assets/misc_technical_documents/transit_sirna_high_efficiency_sirna_delivery.pdf
    MTR007 Rev. 9/04 Mirus Bio Corporation • 888.530.0801 or 608.441.2852 • www.mirusbio.com Technical Report TransIT® siRNA Transfection Reagents for High Efficiency siRNA Delivery In Vitro Robert Brazas, Shyla Millard, Tracy Kawleski, and James Hagstrom

Dynamic PolyConjugates for targeted in vivo delivery of ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1941806/
    Aug 07, 2007 · Effective in vivo delivery of siRNA to the appropriate target cell is an essential component of these siRNA-based applications. Accordingly, a variety of nonviral (4 –14) and viral (15 –17) systems are being developed for delivery of siRNA to liver, tumors, and other tissues in vivo.Author: David B. Rozema, David L. Lewis, Darren H. Wakefield, So C. Wong, Jason J. Klein, Paula L. Roesch, S...

Progress in MicroRNA Delivery - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891846/
    Dec 28, 2013 · I. Discovery and Action of miRNAs. MicroRNAs (miRNAs) are one of a growing number of non-coding RNA molecules that act within a cell [1, 2].Noncoding RNAs include miRNA, small interfering RNA (siRNA), ribozymes, among others [].Both miRNA and siRNA interact with messenger RNA (mRNA), typically marking the mRNA for degradation as will be described in this review.Author: Yu Zhang, Zaijie Wang, Richard A. Gemeinhart

Optimizing siRNA Transfection for RNAi Thermo Fisher ...

    https://www.thermofisher.com/us/en/home/references/ambion-tech-support/rnai-sirna/tech-notes/optimizing-sirna-transfection-for-rnai.html
    Quite often, the success or failure of an siRNA experiment hinges on siRNA delivery. siRNAs can be transiently transfected using commonly available transfection reagents. However, high efficiency transfection of siRNA is not trivial; therefore, the utility of RNAi in …

Using Transfection for siRNA Delivery

    https://fujifilmcdi.com/assets/CDI_iCellCM_siRNA_AP-CMCRNAI1310281.pdf
    Using Transfection for siRNA Delivery . Introduction Delivery of exogenous small interfering RNA (siRNA) in cultured cells is an effective method to modulate target gene expression via RNA interference (RNAi). Several siRNA delivery systems and reagents are available depending on the cell

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