Midazolam Nasal Delivery

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Pharmacokinetics and pharmacodynamics of nasally delivered ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883753/
    Nasal application of midazolam (MDZ) has been studied for sedation before surgical, dental or diagnostic procedures, and for treatment of seizures in children and adult patients. Since no nasal preparation is commercially available, MDZ solution for injection has been used in many studies for nasal delivery in paediatric and adult patients [1–7].Author: Manuel Haschke, Katja Suter, Sarah Hofmann, Robert Witschi, Johannes Fröhlich, Georgios Imanidis, Jü...

Administering Nasal or Buccal Midazolam

    https://www.epilepsy.org.au/wp-content/uploads/2019/02/Fact-Sheet-Administering-Midazolam.pdf
    Midazolam belongs to a group of medications called benzodiazepines. It is a short-acting sedative that can be used in the emergency treatment of seizures. When is it used for seizures? Midazolam is prescribed for some people who experience severe, cluster or prolonged seizures. which may develop into status epilepticus.

MAD Nasal™ Intranasal Mucosal Atomization Device US ...

    https://www.teleflex.com/usa/en/product-areas/anesthesia/atomization/mad-nasal-device/index.html
    The MAD Nasal ™ Intranasal Mucosal Atomization Device from Teleflex is the safe and painless way to deliver medications*. Atomizes in any position The soft, conical plug on the tip forms a seal with the nostril, preventing expulsion of fluid

Nayzilam (Midazolam Nasal Spray): Uses, Dosage, Side ...

    https://www.rxlist.com/nayzilam-drug.htm
    May 22, 2019 · NAYZILAM is supplied as a solution of midazolam. Each single-dose nasal spray unit delivers 5 mg of midazolam in 0.1 mL of solution. NAYZILAM is supplied in boxes of 2 nasal spray units ( NDC 72178-100-02), each contained within an individual blister pack.

Evaluation of Intranasal Midazolam in Children Undergoing ...

    https://journals.lww.com/jpgn/Fulltext/1997/09000/Evaluation_of_Intranasal_Midazolam_in_Children.4.aspx
    In this study, intranasal midazolam was delivered by nasal spray as compared with delivery by nasal drops reported in other investigations (8-10,12,14-18,27,28). Before beginning enrollment, we determined that patients preferred this spray device because it reduced the discomfort caused by instilling undiluted midazolam into the nares.

Intranasal Delivery of Two Benzodiazepines, Midazolam and ...

    https://www.researchgate.net/profile/Amnon_Sintov/publication/266211157_Intranasal_Delivery_of_Two_Benzodiazepines_Midazolam_and_Diazepam_by_a_Microemulsion_System/links/574c10cb08ae7dff1bcfe907/Intranasal-Delivery-of-Two-Benzodiazepines-Midazolam-and-Diazepam-by-a-Microemulsion-System.pdf
    Intranasal Delivery of Two Benzodiazepines, Midazolam and Diazepam, by a Microemulsion System 181 vulsions can be used only in children and in a few cases in adolescents; 3) it is highly ...

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