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https://www.ncbi.nlm.nih.gov/pubmed/22138068
Jul 20, 2012 · Microvesicles and exosomes: opportunities for cell-derived membrane vesicles in drug delivery. van Dommelen SM(1), Vader P, Lakhal S, Kooijmans SA, van Solinge WW, Wood MJ, Schiffelers RM. Author information: (1)Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands.Author: S M van Dommelen, P Vader, S Lakhal, Kooijmans Saa., W W van Solinge, Wood Mja., R M Schiffelers
https://www.sciencedirect.com/science/article/pii/S0168365915301322
The uptake of microvesicles and exosomes by the autologous prostate cancer cells was assessed by flow cytometry and confocal microscopy. The EVs were loaded with Paclitaxel and the effectiveness of EV-mediated drug delivery was assessed with viability assays.Author: Heikki Saari, Elisa Lázaro-Ibáñez, Tapani Viitala, Elina Vuorimaa-Laukkanen, Pia Siljander, Marjo Yl...
https://www.sciencedirect.com/science/article/pii/S0169409X16300576
Extracellular vesicles (EVs) are cell-derived membrane vesicles, and represent an endogenous mechanism for intercellular communication. Since the discovery that EVs are capable of functionally transferring biological information, the potential use of EVs as drug delivery vehicles has gained considerable scientific interest.Author: Pieter Vader, Emma A. Mol, Gerard Pasterkamp, Raymond M. Schiffelers
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951582/
Mar 08, 2016 · The exploitation of exosomes as drug delivery vehicles offers important advantages compared to other nanoparticulate drug delivery systems such as liposomes and polymeric nanoparticles; exosomes are non-immunogenic in nature due to similar composition as body׳s own cells.Author: Dinh Ha, Ningning Yang, Venkatareddy Nadithe
https://www.hindawi.com/journals/sci/2016/5029619/
Extracellular vesicles (EVs), such as microvesicles and exosomes, are membranous structures containing bioactive material released by several cells types, including mesenchymal stem/stromal cells (MSCs). Increasing lines of evidences point to EVs as paracrine mediators of the beneficial effects on tissue remodeling associated with cell therapy.Author: Giuliana Di Rocco, Silvia Baldari, Gabriele Toietta
https://www.exosome-rna.com/extracellular-vesicles-for-drug-delivery/
Nov 01, 2016 · Extracellular vesicles (EVs) are cell-derived membrane vesicles, and represent an endogenous mechanism for intercellular communication. Since the discovery that EVs are capable of functionally transferring biological information, the potential use of EVs as drug delivery vehicles has gained considerable scientific interest.
https://www.frontiersin.org/articles/10.3389/fsufs.2019.00023/full
Apr 16, 2019 · Various kinds of vesicles have been produced from plant, animal and inorganic materials for use as delivery vehicles especially in functional food formulation. However, major drawbacks associated with most of them include issues with sustainability, safety, biocompatibility, biorecognition, stability, bioavailability, bioadhesion, generation of reactive species, inefficient encapsulation and ...Author: Precious Akuma, Ogadimma D. Okagu, Chibuike C. Udenigwe
https://www.beckman.com/resources/research-areas/exosomes/drug-delivery-with-exosome-nanoparticles
Targeting Efficient Drug Delivery With Exosome Nanoparticles. Exosomes are small vesicles (typically 30-120 nm), formed through the inward budding of endocytic compartments and secreted through fusion of these vesicle-containing endosomes with the plasma membrane.
http://sci.amegroups.com/article/view/16734/16967
Engineering of extracellular vesicles as drug delivery vehicles Extracellular vesicles (EVs) are secreted membrane-enclosed nano-sized particles (40–1,000 nm) that deliver biological information between cells.Author: Sung-Man Kim, Han-Soo Kim
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