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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255415/
The microsponge drug delivery system offers entrapment of its ingredients and is believed to contribute toward reduced side effects, improved stability, increased elegance, and enhanced formulation flexibility.
https://www.researchgate.net/publication/321293435_Microsponge_Drug_Delivery_System
Microsponges drug delivery approach (MDA) has been introduced in topical products to facilitate the controlled and targeted release of active drug into the skin to decrease systemic exposure and...Author: Tushar Saha
https://www.pharmatutor.org/articles/recent-advancement-microsponge-drug-delivery-system-review
Microsponge do not pass through the skin (capable of holding four times their weight in skin secretions). Rather, they collect in the tiny nooks and crannies of skin and slowly release the entrapped drug, as the skin needs it. The microsponge system can prevent excessive accumulation of ingredients within the epidermis and the dermis.
http://ijpsr.com/bft-article/novel-approach-microsponge-drug-delivery-system/?view=fulltext
The microsponge based drug delivery system is a unique technology for controlled release and enhanced drug deposition in the skin while minimizing transdermal penetration of topically active agents. Drug loaded microsponge consist of microporous beads, typically 10-25 μm in diameter.
https://pdfs.semanticscholar.org/ffe0/21daa40e189eabff2333fff29376941132b9.pdf
microsponge drug delivery system (MDS) releases its active ingredient on a time mode and also in response to other stimuli such as rubbing, temperature,and pH (Vyas and Khar, 2002).
https://www.slideshare.net/BalasahebKarad/microsponge-drug-delivery-system-59413789
Mar 11, 2016 · Microsponge as Topical drug delivery The human skin is a large and complex organ that protects internal tissue from environmental exposure. As the interface between the organism and the external world, the skin is susceptible to injuries from the environment or from other organisms.
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