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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720159/
Jun 30, 2008 · Microbubbles enhance ultrasound energy deposition in the tissues and serve as cavitation nuclei, increasing intracellular drug delivery. DNA delivery and successful tissue transfection is observed in the areas of the body where ultrasound is applied after intravascular administration of microbubbles and plasmid DNA.Author: Sophie Hernot, Sophie Hernot, Alexander L. Klibanov
https://www.ncbi.nlm.nih.gov/pubmed/18486268
Jun 30, 2008 · Microbubbles enhance ultrasound energy deposition in the tissues and serve as cavitation nuclei, increasing intracellular drug delivery. DNA delivery and successful tissue transfection are observed in the areas of the body where ultrasound is applied after intravascular administration of microbubbles and plasmid DNA.Author: Sophie Hernot, Sophie Hernot, Alexander L. Klibanov
https://www.sciencedirect.com/science/article/abs/pii/S0169409X08000811
Jun 30, 2008 · Microbubbles enhance ultrasound energy deposition in the tissues and serve as cavitation nuclei, increasing intracellular drug delivery. DNA delivery and successful tissue transfection are observed in the areas of the body where ultrasound is applied after intravascular administration of microbubbles and plasmid DNA.Author: Sophie Hernot, Sophie Hernot, Alexander L. Klibanov
https://www.researchgate.net/publication/5364818_Microbubbles_in_Ultrasound-Triggered_Drug_and_Gene_Delivery
68 Microbubbles are used as an ultrasound contrast agent because they scatter sonic waves more than blood, but they have recently garnered attention as agents for drug delivery and gene therapy ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084724/
Microbubbles play an important multi-functional role in ultrasound mediated drug delivery. These microbubbles are currently used as contrast agents for preclinical and clinical ultrasound imaging to enhance the contrast between blood (in which the microbubbles circulate…Author: Tzu-Yin Wang, Katheryne E. Wilson, Steven Machtaler, Jurgen K. Willmann
https://www.sciencedirect.com/science/article/pii/S0022354916329835
If such MBs have been loaded with a drug or gene therapy vector, ultrasound targeted microbubble destruction (UTMD) can be used to locally deliver and release the transported substance. As MBs act as cavitation nuclei, they lower the required US energy to intensity levels, mandated by the FDA. 10, 11Author: Steliyan Tinkov, Raffi Bekeredjian, Gerhard Winter, Conrad Coester
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2497170/
Microbubbles have been shown to be able to carry drugs and genes, and destruction of the bubbles by ultrasound will result in local release of their contents. Furthermore, ligands can be attached so that they can be targeted to a specific target tissue.Author: L.J.M. Juffermans, P.A. Dijkmans, R.J.P. Musters, A. van Wamel, A. Bouakaz, F.J. ten Cate, L. Deelma...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC538251/
Nov 16, 2004 · Mechanisms for Target Drug Delivery Using Microbubbles. Two possible strategies for delivering drugs and genes with microbubbles are emerging. The first consists on the ultrasound-mediated microbubble destruction, which is based on the cavitation of microbubbles induced by ultrasound application, and the second is the direct delivery of substances bound to microbubbles in …Author: Jeane M Tsutsui, Feng Xie, Richard Thomas Porter
https://res.mdpi.com/d_attachment/molecules/molecules-23-02210/article_deploy/molecules-23-02210.pdf
cationic to apply electrostatic interactions for gene delivery. This method facilitates the gene therapy and various researchers have aimed at using MNBs to enhance targeted gene delivery [17,47]. Finally, MNBs can be co-administered with bioactive substances, using high-intensity ultrasound to enhance
https://en.wikipedia.org/wiki/Microbubble
Microbubbles may be used for drug delivery, biofilm removal, membrane cleaning /biofilm control and water/waste water treatment purposes. They are also produced by the movement of a ship’s hull through water, creating a bubble layer; this may interfere with the use of sonar because of the tendency of the layer to absorb or reflect sound waves.
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