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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC538251/
Nov 16, 2004 · Mechanisms for Target Drug Delivery Using Microbubbles. Two possible strategies for delivering drugs and genes with microbubbles are emerging. The first consists on the ultrasound-mediated microbubble destruction, which is based on the cavitation of microbubbles induced by ultrasound application, and the second is the direct delivery of substances bound to microbubbles in …Author: Jeane M Tsutsui, Feng Xie, Richard Thomas Porter
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084724/
Ultrasound mediated drug delivery using microbubbles is a safe and noninvasive approach for spatially localized drug administration. This approach can create temporary and reversible openings on cellular membranes and vessel walls (a process called “sonoporation”), allowing for enhanced transport of therapeutic agents across these natural barriers.Author: Tzu-Yin Wang, Katheryne E. Wilson, Steven Machtaler, Jurgen K. Willmann
https://www.news-medical.net/life-sciences/What-are-Microbubbles.aspx
Feb 26, 2019 · Microbubbles are small, gas-filled bubbles, typically between 0.5µm and 10µm in diameter, that are widely used as contrast agents in medical imaging and …
https://www.youtube.com/watch?v=Z6BMYNXbwLU
Oct 21, 2015 · Using ultrasound waves, researchers have found a way to enable rapid delivery of drugs to the gastrointestinal (GI) tract. This approach could make it easier...
https://cardiovascularultrasound.biomedcentral.com/articles/10.1186/1476-7120-2-23
Nov 16, 2004 · Ultrasound-mediated microbubbles destruction has been proposed as an innovative method for noninvasive delivering of drugs and genes to different tissues. Microbubbles are used to carry a drug or gene until a specific area of interest is reached, and then ultrasound is used to burst the microbubbles, causing site-specific delivery of the bioactive materials. Furthermore, the ability of …
https://www.medgadget.com/2017/08/ultrasound-microbubbles-targeted-chemotherapy-delivery.html
Researchers in Norway have developed a chemotherapy delivery system consisting of microbubbles containing drug-loaded nanoparticles. When the researchers apply ultrasound to the microbubbles in a ...
https://www.nibib.nih.gov/news-events/newsroom/targeted-drug-delivery-microbubbles
Sep 16, 2005 · In current studies, the ultrasound pulse sequence shatters the lipospheres releasing a dye which then adheres to the vessel wall. This approach provides greater accuracy for targeted drug delivery. Future studies will include a drug rather than a dye.Images courtesy of Dr. Katherine Ferrara, University of California-Davis.
https://www.sciencedirect.com/science/article/pii/S0169409X08000811
Microbubbles are manufactured from biocompatible materials, they can be injected intravenously, and some are approved for clinical use. Microbubbles can be destroyed by ultrasound irradiation. This destruction phenomenon can be applied to targeted drug delivery and enhancement of drug action.Author: Sophie Hernot, Sophie Hernot, Alexander L. Klibanov
https://pubs.acs.org/doi/10.1021/acs.langmuir.8b04008
Biomedical microbubbles stabilized by a coating of magnetic or drug-containing nanoparticles show great potential for theranostics applications. Nanoparticle-coated microbubbles can be made to be stable, to be echogenic, and to release the cargo of drug-containing nanoparticles with an ultrasound trigger. This Article reviews the design principles of nanoparticle-coated microbubbles for ...Author: Akaki Jamburidze, Axel Huerre, Diego Baresch, Vincent Poulichet, Marco De Corato, Valeria Garbin
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