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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC538251/
Nov 16, 2004 · Mechanisms for Target Drug Delivery Using Microbubbles. Two possible strategies for delivering drugs and genes with microbubbles are emerging. The first consists on the ultrasound-mediated microbubble destruction, which is based on the cavitation of microbubbles induced by ultrasound application, and the second is the direct delivery of substances bound to microbubbles in …Author: Jeane M Tsutsui, Feng Xie, Richard Thomas Porter
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084724/
Ultrasound mediated drug delivery using microbubbles is a safe and noninvasive approach for spatially localized drug administration. This approach can create temporary and reversible openings on cellular membranes and vessel walls (a process called “sonoporation”), allowing for enhanced transport of therapeutic agents across these natural barriers.Author: Tzu-Yin Wang, Katheryne E. Wilson, Steven Machtaler, Jurgen K. Willmann
https://www.news-medical.net/life-sciences/What-are-Microbubbles.aspx
Feb 26, 2019 · Microbubbles are small, gas-filled bubbles, typically between 0.5µm and 10µm in diameter, that are widely used as contrast agents in medical imaging and as carriers for targeted drug delivery ...
https://www.sciencedirect.com/science/article/pii/S0168365914007342
Whereas microbubble cavitation in an ultrasonic field has been studied extensively, the biophysical mechanisms leading to enhanced drug delivery are still a matter of debate. The formation of membrane pores, i.e. sonoporation, is generally accepted as main mechanism by which drugs enter cells during ultrasound application.Author: Ine De Cock, Elisa Zagato, Kevin Braeckmans, Ying Luan, Nico de Jong, Stefaan C. De Smedt, Ine Lenta...
https://www.nature.com/articles/s41598-020-62410-3
Mar 25, 2020 · Targeted Drug Delivery of Microbubble to Arrest Abdominal Aortic Aneurysm Development: A Simulation Study Towards Optimized Microbubble Design Skip to main content Thank you for visiting nature.com.
https://cardiovascularultrasound.biomedcentral.com/articles/10.1186/1476-7120-2-23
Nov 16, 2004 · Ultrasound-mediated microbubbles destruction has been proposed as an innovative method for noninvasive delivering of drugs and genes to different tissues. Microbubbles are used to carry a drug or gene until a specific area of interest is reached, and then ultrasound is used to burst the microbubbles, causing site-specific delivery of the bioactive materials. Furthermore, the ability of …
https://www.scintica.com/new-journal-article-ultrasound-induced-microbubble-cavitation-via-a-transcanal-or-transcranial-approach-facilitates-inner-ear-drug-delivery/
In a recent paper published in JCI Insight, researchers have demonstrated for the first time the feasibility of applying Ultrasound-induced Microbubble Cavitation via the external auditory canal as a technique to increase the efficiency of drug delivery to the inner ear.
https://www.youtube.com/watch?v=Z6BMYNXbwLU
Oct 21, 2015 · Using ultrasound waves, researchers have found a way to enable rapid delivery of drugs to the gastrointestinal (GI) tract. This approach could make it …
https://jtultrasound.biomedcentral.com/articles/10.1186/2050-5736-1-10
Jul 01, 2013 · Ultrasound-targeted microbubble destruction (UTMD) is a promising technique for non-invasive, targeted drug delivery, and its applications in chemotherapeutic drug delivery to solid tumors have attracted growing interest. Ultrasound, which has been conventionally used for diagnostic imaging, has evolved as a promising tool for therapeutic applications mainly because of its ability to be ...Author: Hong Chen, Joo Ha Hwang
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/microbubble
16.3.1.3 Microbubble drug delivery. Microbubbles can provide deep penetration into the body tissues; however, their cargo space is generally small and is usually confined to the nonfluorous shell. The drug-loading capacity can be increased by increasing the size of the shell but only at the expense of image sensitivity, as larger shells are ...
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