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https://www.nature.com/articles/ncpcardio0447
Mar 01, 2006 · There are several strategies for cell delivery in cardiac stem cell therapy. The cells can be delivered through coronary arteries, coronary veins, or peripheral veins. Alternatively, direct intramyocardial injection can be performed, using a surgical, transendocardial, or transvenous approach.Author: Emerson C Perin, Javier López
https://www.researchgate.net/publication/7275222_Methods_of_stem_cell_delivery_in_cardiac_diseases
Methods of stem cell delivery in cardiac diseases Article · Literature Review in Nature Clinical Practice Cardiovascular Medicine 3 Suppl 1(1, supplement):S110-3 · April 2006 with 46 Reads
https://www.hindawi.com/journals/bmri/2013/547902/
Cell types currently investigated for cellular delivery include embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and adult stem cell lineages such as skeletal myoblasts, bone-marrow-derived stem cells (BMSCs), mesenchymal stem cells (MSCs), and cardiac stem cells (CSCs).Author: Calvin C. Sheng, Li Zhou, Jijun Hao
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047684/
Phases I and II clinical trials have been published for a variety of biologics utilizing four methods of delivery: systemic infusion, intracoronary infusion, transvenous coronary sinus, and intramyocardial. This review discusses the advantages and disadvantages of …Author: Nabil Dib, Harris Khawaja, Samantha Varner, Megan McCarthy, Ann Campbell
https://www.webmd.com/heart-disease/heart-failure/stem-cells-heart-failure-treatment
Scientists have zeroed in on a few specific kinds of cells that may be helpful: Bone marrow mononuclear cells: A mixture of cells that comes from your own bone marrow. Cardiac-derived stem cells: Ones found in heart tissue. Mesenchymal stromal cells: They're usually taken from bone marrow, fat, or umbilical cord blood.Author: Stephanie Langmaid
https://www.eurostemcell.org/what-diseases-and-conditions-can-be-treated-stem-cells
The most well-established and widely used stem cell treatment is the transplantation of blood stem cells to treat diseases and conditions of the blood and immune system, or to restore the blood system after treatments for specific cancers. The US National Marrow Donor Program has a full list of diseases treatable by blood stem cell transplant.
https://www.sciencedirect.com/book/9780128018880/stem-cell-and-gene-therapy-for-cardiovascular-disease
The successful application of autologous and allogeneic stem cell therapy for heart disease has prompted more recent preclinical, and a few clinical, studies examining the safety and efficacy of combining two different types of stem cells. ... The newest method of delivery is by retrograde injection via the coronary sinus or venous system of ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708059/
In order to be suitable for cardiac repair, stem cell-derived cardiac cells should resemble the original cardiac cell types and be able to integrate in the damaged heart. Integration requires administration of stem cell-derived cardiac cells at the right time using the right mode of delivery.Author: Bastiaan C du Pré, Pieter A Doevendans, Linda W van Laake
https://www.slideshare.net/RashedulIslam44/cardiovascular-stem-cell-therapy
Mar 10, 2016 · Delivery options for stem cell transfer modalities to the heart. 11. • The homing of stem cells has been performed via local delivery of various chemotactic factors • Homing factor, stromal derived factor 1 alpha (SDF-1α) demonstrated enhanced recruitment of c-kit+ stem cells to myocardium in a mouse infarct model.
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