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https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.201606134
Mar 29, 2017 · Important research progress of metal–organic framework (MOF)‐based drug/cargo delivery systems and their applications in the field of materials science and …Author: Ming-Xue Wu, Ying-Wei Yang
https://www.nature.com/articles/nmat2608
Dec 13, 2009 · An important challenge in medicine is the efficient delivery of drugs in the body using non-toxic nanocarriers. Porous metal–organic frameworks with imaging …Author: Patricia Horcajada, Tamim Chalati, Christian Serre, Brigitte Gillet, Catherine Sebrie, Tarek Baati, ...
https://pubs.rsc.org/en/content/articlelanding/2018/tb/c7tb02970e
Development of a controllable drug delivery system is imperative and important to reduce the side-effects and enhance the therapeutic efficacy of drugs. Metal–organic frameworks (MOFs) and nanoscale MOFs (NMOFs), as porous hybrids constructed by polydentate bridging ligands and metal-connecting nodes, have a Recent Review Articles
https://www.northeastern.edu/rise/presentations/a-new-metal-organic-framework-for-drug-delivery/
The use of nanoparticles (NPs) in cancer and other medical applications seeks a set of relevant features: enhancement of the drug therapeutic action by increasing efficacy and/or decreasing toxicities; improvement of the pharmaceutical properties of drugs such as stability or circulating half-life ...
https://www.dovepress.com/metal-organic-frameworks-as-a-drug-delivery-system-for-flurbiprofen-peer-reviewed-fulltext-article-DDDT
Introduction. Over the last 20 years, a number of different nanoparticle-based strategies have been developed to improve the efficacy of conventional drug delivery. 1,2 Porous and tunable hybrid materials, metal organic frameworks (MOFs), are promising candidates as potential drug carriers, because of their remarkably large surface areas and excessively high porosities. 3,4 The adjustment …
https://chu468blog.wordpress.com/
Introduction to Metal-organic Frameworks. Over the past 25 years, metal-organic frameworks (MOFs), also known as porous coordination polymers, have attracted a vast amount of interest due to the fact their synthesis can be directed to form certain topologies. 1 In addition to their directed synthesis, the extensive applications of MOFs are also of interest.
https://www.dovepress.com/metal-organic-frameworks-as-a-drug-delivery-system-for-flurbiprofen-peer-reviewed-article-DDDT
Metal organic frameworks as a drug delivery system for flurbiprofen Muder AL Haydar,1,2 Hussein Rasool Abid,3,4 Bruce Sunderland,2 Shaobin Wang5,6 1Pharmaceutics Department, College of the Pharmacy, University of Kerbala, Kerbala, Iraq; 2Pharmaceutics Department, School of Pharmacy, Faculty of Health Sciences, Curtin University, Perth, WA, Australia; 3Department of Chemical …
https://www.researchgate.net/publication/337248847_Metal-organic_frameworks_for_stimuli-responsive_drug_delivery
Drug delivery using metal-organic frameworks (MOF) has elicited interest in their biocompatibility; however, few studies have been conducted on their stability in common buffers, cell media, and ...
https://chu468blog.wordpress.com/chemistry-of-mofs/
Metal-organic frameworks are a sub-class of coordination polymer and defined as repeating units of metal ions, or clusters, linked by organic molecules. These organic molecules are often multidentate, such as the hexadentate 5,5’,5’’-(1,3,5-triazine-2,4,6-triyl)tris(azanediyl)triisophthalate (TATAT) and 1,4-benzezedicarboxylate (BDC).5,6 Fig. 1: TATAT (left) and BDC ligands The vast ...
https://pubs.rsc.org/en/content/articlelanding/2015/cc/c5cc05237h
Amorphous metal–organic frameworks for drug delivery ... followed by amorphization of the framework by ball-milling. We show controlled release of calcein over more than 30 days, compared with the 2 day release period from crystalline UiO-66.
https://www.sciencedirect.com/science/article/pii/S014296121730039X
Positioning metal-organic framework nanoparticles within the context of drug delivery – A comparison with mesoporous silica nanoparticles and dendrimers Author links open overlay panel Stefan Wuttke a Marjorie Lismont b Alberto Escudero c Bunyarat Rungtaweevoranit d …
https://www.nature.com/articles/s41467-018-03650-w
He, C., Lu, K., Liu, D. & Lin, W. Nanoscale metal-organic frameworks for the co-delivery of cisplatin and pooled siRNAs to enhance therapeutic efficacy in drug-resistant ovarian cancer cells. J. Am.
http://www.eurekaselect.com/node/172733/article/metal-organic-framework-mof-based-drug-delivery
Keywords:Drug delivery, Metal-organic framework, nanocarriers, matrix, toxicity, anticancer Abstract:Background: Developing a controllable drug delivery system is imperative and important to reduce side effects and enhance the therapeutic efficacy of drugs. Metal-organic frameworks (MOFs)—an emerging class of hybrid porous materials built ...
https://lvts.fr/wp-content/uploads/2018/06/2018_Nanoparticles-of-Metal-Organic-Frameworks-On-the-Road-to-In-Vivo-Efficacy-in-Biomedicine.pdf
the drug delivery performances for the treatment of several diseases.[24,34] Moreover, the high and regular porosity and the unique combination of well-dispersed metal sites and organic groups within the framework of nanoMOFs, combined with the low toxicity of …
https://advances.sciencemag.org/content/6/13/eaaz6108.full
Small interfering RNA (siRNA) is a powerful tool for gene silencing that has been used for a wide range of biomedical applications, but there are many challenges facing its therapeutic use in vivo. Here, we report on a platelet cell membrane–coated metal-organic framework (MOF) nanodelivery platform for the targeted delivery of siRNA in vivo.
https://www.researchgate.net/publication/315777336_Metal-Organic_Framework_MOF-Based_DrugCargo_Delivery_and_Cancer_Therapy
Metal-Organic Framework (MOF)-Based Drug/Cargo Delivery and Cancer Therapy Article in Advanced Materials 29(23):1606134 · June 2017 with 1,052 Reads How we measure 'reads'
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