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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522861/
In particular, mesoporous silica nanoparticles (MSNs) are widely used as a delivery reagent because silica possesses favorable chemical properties, thermal stability, and biocompatibility. The unique mesoporous structure of silica facilitates effective loading of drugs and their subsequent controlled release of the target site.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.201902634
Researchers are developing novel nanoparticles for both diagnostic applications using imaging technology and treatment purposes through drug delivery technologies. Among all the available nanoparticles, inorganic mesoporous silica nanoparticles are the newcomers to the field, contributing with their unique and superlative properties.Author: Miguel Manzano, Miguel Manzano, María Vallet‐Regí, María Vallet‐Regí
https://www.sciencedirect.com/science/article/pii/B9780128140338000114
Mesoporous Silica Drug-Delivery Systems for Penicillin Antibiotics Penicillin is a group of β-lactam antibiotics still widely in use, even though many bacteria have developed resistance. Penicillin antibiotics are among the first medications effective against bacterial infections caused by streptococci and staphylococci.Author: Raul-Augustin Mitran, Mihaela Deaconu, Cristian Matei, Daniela Berger
https://www.researchgate.net/publication/335661321_Mesoporous_Silica_Nanoparticles_for_Drug_Delivery
Gated mesoporous silica nanoparticles can deliver payload upon the application of a predefined stimulus, and therefore are promising drug delivery systems.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523761/
Apr 01, 2019 · Consequently, mesoporous silica particles have recently been highlighted as ideal carriers for poorly water-soluble drugs [18,19,20], which, despite a high potency, often have severely limited efficacy as a result of the fact that the amount of soluble drug is not high enough for reaching therapeutic concentrations.Author: Tina Gulin-Sarfraz, Sofia Jonasson, Elisabeth Wigenstam, Eva von Haartman, Anders Bucht, Jessica M. ...
https://www.cell.com/molecular-therapy-family/molecular-therapy/pdf/S1525-0016(16)32523-0.pdf
Mesoporous Silica Nanoparticles as Drug Delivery Systems for Targeted Inhibition of Notch Signaling in Cancer
https://pubs.acs.org/doi/10.1021/cm402592t
Oct 03, 2013 · Nanosized mesoporous silica particles with high colloidal stability attract growing attention as drug delivery systems for targeted cancer treatment and as bioimaging devices. This Perspective describes recent breakthroughs in mesoporous silica nanoparticle design to demonstrate their high potential as multifunctional drug delivery nanocarriers.Author: Christian Argyo, Veronika Weiss, Christoph Bräuchle, Thomas Bein
http://web.ics.purdue.edu/~jfleary/nanomedicine_course_2011/Lecture_5%20Core%20materials/Lecture%205%20References/Slowing_Mesoporous_NP_drug%20delivery-sensing.pdf
opment of controlled release and drug delivery devices using mesoporous silica nanomaterials, the effects of these materials on cellular development and propagation, and the difference in develop- ment between normal and cancer cells with the ultimate goal of controlling the release of antitumor drugs in cancer cells.
https://www.sciencedirect.com/science/article/pii/S0169409X08000951
Among many structurally stable materials that have been investigated for drug delivery, silica materials with defined structures and surface properties are known to be biocompatible. Silica is often the material of choice to enable the biological use of inorganic nanoparticles [2], [3], [4].Author: Igor I. Slowing, Juan L. Vivero-Escoto, Chia-Wen Wu, Victor S.-Y. Lin
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