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https://www.researchgate.net/publication/6247461_Mesoporous_Silica_Nanoparticles_for_Intracellular_Delivery_of_Membrane-Impermeable_Proteins
Mesoporous Silica Nanoparticles for Intracellular Delivery of Membrane-Impermeable Proteins Article in Journal of the American Chemical Society 129(28):8845-9 · August 2007 with 89 Reads
http://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=1320&context=ameslab_pubs
Mesoporous Silica Nanoparticles for Intracellular Delivery of Membrane-Impermeable Proteins Abstract An MCM-41-type mesoporous silica nanoparticle (MSN) material with a large average pore diameter (5.4 nm) is synthesized and characterized. The in vitro uptake and release profiles of cytochromec by the MSN were investigated.
http://onlinelibrary.wiley.com/doi/10.1002/biot.201600408/full
Jan 11, 2017 · 2 Mesoporous silica nanoparticles: Ideal candidates for protein delivery. Protein delivery has been explored using a wide variety of materials. In 2005, delivery of a cell membrane-impermeable protein, cytochrome c (Cyt c), using single-walled carbon nanotubes was demonstrated by Kam etAuthor: Gauri V Deodhar, Marisa L Adams, Brian G Trewyn
https://www.sciencedirect.com/science/article/pii/B9780123918604000033
For hydrophilic drugs, the delivery of a neurotransmitter (ATP) and an antibiotic (vancomycin) to astrocyte cells by pore-capped MSN materials has been demonstrated (Lai et al., 2003).The procedures for the synthesis of drug loaded, cadmium sulfide nanoparticle (CdS) capped MSN are as follows: 2-(propyldisulfanyl) ethylamine-functionalized mesoporous silica nanospheres (linker-MSN) are ...Author: I-Ju Fang, Brian G. Trewyn
https://www.sciencedirect.com/science/article/pii/S1549963414005462
From the Clinical Editor. This comprehensive review presents recent advances in mesoporous silica nanoparticles assisted drug delivery systems, including both immediate and sustained delivery systems as well as controlled release and targeted drug delivery systems.Author: Ying Wang, Qinfu Zhao, Ning Han, Ling Bai, Jia Li, Jia Liu, Erxi Che, Liang Hu, Qiang Zhang, Tongyin...
https://www.nature.com/articles/nnano.2007.108
Apr 29, 2007 · Surface-functionalized silica nanoparticles can deliver DNA1,2,3,4,5,6,7,8 and drugs9,10,11,12,13,14,15 into animal cells and tissues. However, …Author: François Torney, Brian G. Trewyn, Victor S.-Y. Lin, Kan Wang
http://iopscience.iop.org/article/10.1088/0957-4484/21/22/225101/pdf
Intracellular protein delivery by hollow mesoporous silica capsules with a large surface hole Ji-Sun Lim, Kiwon Lee, Jong-Nam Choi et al.-pH-responsive nanovalves based on hollow mesoporous silica spheres for controlled release of corrosion inhibitor Tao Chen and JiaJun Fu-Targeted anticancer prodrug with mesoporous silica nanoparticles as vehicles
https://lib.dr.iastate.edu/cgi/viewcontent.cgi?article=1915&context=etd
CHAPTER 2. MESOPOROUS SILICA NANOPARTICLES FOR INTRACELLULAR CONTROLLED DRUG DELIVERY Abstract 3 1. Introduction 4 2. Synthesis of mesoporous silica nanoparticles 6 2.1 Control of structural properties (size and shape) 7 2.2 Control of surface functionalization 9 3.Author: Juan Luis Vivero-Escoto
https://www.researchgate.net/publication/311691392_Controlled_release_and_intracellular_protein_delivery_from_mesoporous_silica_nanoparticles
Controlled release of intracellular proteins from mesoporous silica nanoparticles is reviewed by Deodhar et al. [12]. The topic of systems biology is covered by the group of Professor Byung-Gee ...
http://www.rsc.org/suppdata/cc/b9/b900559e/b900559e.pdf
Cell-induced Intracellular Controlled Release of Membrane Impermeable Cysteine from a Mesoporous Silica Nanoparticle-based Drug Delivery System Renato Mortera, Juan Vivero-Escoto, Igor I. Slowing, Edoardo Garrone, Barbara Onida and Victor S.-Y. Lin* Reagents and Materials: Tetraethylorthosilicate (TEOS) was purchased from Gelest.
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