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https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.200601191
Apr 20, 2007 · Recent advancements in morphology control and surface functionalization of mesoporous silica nanoparticles (MSNs) have enhanced the biocompatibility of these materials with high surface areas and pore volumes. Several recent reports have demonstrated that the MSNs can be efficiently internalized by animal and plant cells.Author: Igor I. Slowing, Brian G. Trewyn, Supratim Giri, Victor S.-Y. Lin
https://onlinelibrary.wiley.com/doi/pdf/10.1002/adfm.200601191
Apr 20, 2007 · Several recent reports have demonstrated that the MSNs can be efficiently internalized by animal and plant cells. The functionalization of MSNs with organic moieties or other nanostructures brings controlled release and molecular recognition capabilities to these mesoporous materials for drug/gene delivery and sensing applications, respectively.Author: Igor I. Slowing, Brian G. Trewyn, Supratim Giri, Victor S.-Y. Lin
http://web.ics.purdue.edu/~jfleary/nanomedicine_course_2011/Lecture_5%20Core%20materials/Lecture%205%20References/Slowing_Mesoporous_NP_drug%20delivery-sensing.pdf
opment of controlled release and drug delivery devices using mesoporous silica nanomaterials, the effects of these materials on cellular development and propagation, and the difference in develop- ment between normal and cancer cells with the ultimate goal of controlling the release of antitumor
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943960/
Dec 25, 2017 · Mesoporous Silica Nanoparticles as Drug Delivery Systems MSNs exhibit unique characteristics that make them ideal nanocarriers to host, protect and transport drugs to the target site. It is feasible to incorporate targeting agents in the external surface of MSNs to direct them to the unhealthy tissues aimed at increasing specificity and therefore diminishing undesired side effects.Author: María Vallet-Regí, Montserrat Colilla, Isabel Izquierdo-Barba, Miguel Manzano
https://www.researchgate.net/publication/228030942_Mesoporous_Silica_Nanoparticles_for_Drug_Delivery_and_Biosensing_Applications
Mesoporous silica nanoparticles (MSNs) are attractive nanocarriers due to their biodegradable, biocompatible, and relative malleable porous frameworks that can be functionalized for enhanced...
https://pubs.acs.org/doi/10.1021/ja206998x
Nanotechnology has the potential to impact many long-standing challenges in medicine, such as selective drug delivery and sensitive detection of disease. (1-4) In recent years, mesoporous silica nanoparticles (MSNPs) have attracted attention as a promising component of multimodal nanoparticle systems.Author: Neetu Singh, Amrita D. Karambelkar, Luo Gu, Kevin Yu-Ming Lin, Jordan S. Miller, Christopher S. Chen...
https://www.sciencedirect.com/science/article/pii/S2211383517304926
Besides conventional drug delivery, mesoporous silica can also be applied as carrier for gene transfection. It is well known that carriers play an important role in gene delivery, since the naked nucleic acids show little penetration of cell membranes 100. There are two main gene delivery systems, namely viral and non-viral systems.Author: Yixian Zhou, Guilan Quan, Qiaoli Wu, Xiaoxu Zhang, Boyi Niu, Biyuan Wu, Ying Huang, Xin Pan, Chuanbi...
https://www.sciencedirect.com/science/article/pii/S1549963414005462
In the past decade, mesoporous silica nanoparticles (MSNs) with a large surface area and pore volume have attracted considerable attention for their application in drug delivery and biomedicine.Author: Ying Wang, Qinfu Zhao, Ning Han, Ling Bai, Jia Li, Jia Liu, Erxi Che, Liang Hu, Qiang Zhang, Tongyin...
https://pubs.acs.org/doi/10.1021/cm402592t
Oct 03, 2013 · Mesoporous silica nanoparticles are viewed as a promising and flexible platform for numerous biomedical applications. Nanosized mesoporous silica particles with high colloidal stability attract growing attention as drug delivery systems for targeted cancer treatment and as bioimaging devices.Author: Christian Argyo, Veronika Weiss, Christoph Bräuchle, Thomas Bein
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