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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522861/
Targeted drug delivery of mesoporous silica nanoparticles. Specific targeting is highly attractive as an approach to spontaneously distinguish the site of disease diagnosis and as a result, this technique reduces drug administration dosage and diminishes toxic side-effects of drugs during circulation.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.201902634
Among all the available nanoparticles, inorganic mesoporous silica nanoparticles are the newcomers to the field, contributing with their unique and superlative properties. A brief overview of the most recent progress in the synthesis of mesoporous silica nanoparticles and their use as drug delivery nanocarriers is provided.Author: Miguel Manzano, Miguel Manzano, María Vallet‐Regí, María Vallet‐Regí
https://www.cell.com/molecular-therapy-family/molecular-therapy/pdf/S1525-0016(16)32523-0.pdf
An attractive means for targeted drug delivery is to use drug carriers to which cell-specific targeting ligands have been linked.19,20 Most GSIs are small, hydrophobic molecules which require vehicles able to carry sufficient amounts of hydropho-bic drugs. We have developed mesoporous silica nanoparticles
http://web.ics.purdue.edu/~jfleary/nanomedicine_course_2011/Lecture_5%20Core%20materials/Lecture%205%20References/Slowing_Mesoporous_NP_drug%20delivery-sensing.pdf
the pore and particle morphology of the mesoporous silica materials would have an impact on the controlled release properties. In order to address that question we developed a room-temperature ionic liquid (RTIL)-templated MSN system [10], I. I. Slowing et al./Mesoporous Silica Nanoparticles for Drug Delivery and Biosensing Applications
https://www.sciencedirect.com/science/article/pii/S2211383517304926
Besides conventional drug delivery, mesoporous silica can also be applied as carrier for gene transfection. It is well known that carriers play an important role in gene delivery, since the naked nucleic acids show little penetration of cell membranes 100. There are two main gene delivery systems, namely viral and non-viral systems.Author: Yixian Zhou, Guilan Quan, Qiaoli Wu, Xiaoxu Zhang, Boyi Niu, Biyuan Wu, Ying Huang, Xin Pan, Chuanbi...
https://pubs.acs.org/doi/abs/10.1021/ja901831u
A boronic acid-functionalized mesoporous silica nanoparticle-based drug delivery system (BA-MSN) for glucose-responsive controlled release of both insulin and …Author: Yannan Zhao, Brian G. Trewyn, Igor I. Slowing, Victor S.-Y. Lin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764983/
In particular, mesoporous silica nanoparticles are widely used as a delivery reagent because silica possesses favourable chemical properties, thermal stability and biocompatibility. Currently, sol-gel-derived mesoporous silica nanoparticles in soft conditions are of main interest due to simplicity in production and modification and the capacity ...Author: Sooyeon Kwon, Rajendra K Singh, Roman A Perez, Ensanya A Abou Neel, Ensanya A Abou Neel, Ensanya A A...
https://www.sigmaaldrich.com/technical-documents/articles/materials-science/renewable-alternative-energy/mesoporous-silica.html
The release of drug from the silica carrier is a key performance indicator to consider when employing OMMs (ordered mesoporous materials) for drug dissolution enhancement. The in vitro release of drug from drug–silica samples and the dissolution of the starting fenofibrate are shown in Figure 6.
https://www.slideshare.net/BishopDuhon/mesoporous-silica-nanoparticle-synthesis
May 02, 2016 · Mesoporous Silica Nanoparticle Synthesis 1. Mesoporous Silica Nanoparticle Synthesis Rachel Jones and Jonathan Duhon 2. Background Used for drug delivery due to large surface area and pore size. Acts as a drug carrier for many types of medicine due to low toxicity.
https://www.slideshare.net/VijayMarakatti/mesoporous-materials
Mar 20, 2013 · 1) Sustained Drug Release SystemVirtually any drug within a size range compatible with the size of the meso-channels has potential to be encapsulated and further deliver intracellularly. M. Vallet-Regi, et al. “A New Property of MCM-41: Drug Delivery System”, Chem. Mater. 2001, 13, 308-311. 33. 2. Mesoporous Materials for Bone Tissue Engineering
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