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https://www.sciencedirect.com/science/article/pii/S0169409X08000951
In addition to solid nanoparticles, flexible organic molecules have also been shown to be able to serve as gatekeepers for mesoporous silicas. Tanaka and co-workers first reported a reversible photo-triggered controlled release mesoporous silica (MCM-41) system that could function in organic solvents . Their system took advantage of a ...Author: Igor I. Slowing, Juan L. Vivero-Escoto, Chia-Wen Wu, Victor S.-Y. Lin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522861/
Mesoporous silica nanoparticles (MSNs) have become apparent as a promising and novel drug vehicle due to their unique mesoporous structure that preserving a level of chemical stability, surface functionality and biocompatibility ensure the controlled release, and target drug delivery of a variety of drug molecules.[3,4] Mesoporous silica ...
https://pubs.rsc.org/en/content/articlelanding/2012/cs/c2cs15308d
This review highlights the most recent research progress on silica-based controlled drug delivery systems, including: (i) pure mesoporous silica sustained-release systems, (ii) magnetism and/or luminescence functionalized mesoporous silica systems which integrate targeting and tracking abilities of drug molecules, and (iii) stimuli-responsive ...Author: Piaoping Yang, Piaoping Yang, Shili Gai, Jun Lin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512630/
May 08, 2019 · These drug delivery systems are based on the use of magnetic fields as external stimuli to guide the particles to the tumor environment and to locally increase the temperature, triggering cell death by controlled drug release and/or hyperthermia.79 Superparamagnetic iron oxide nanoparticles are the most used magnetic nanoparticles.Author: Nerea Iturrioz-Rodríguez, Miguel A Correa-Duarte, Mónica L Fanarraga
https://www.sciencedirect.com/science/article/abs/pii/S0169409X08000951
Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers ... We envision that these MSN-based systems have a great potential for a variety of drug delivery applications, such as the site-specific delivery and intracellular controlled release of drugs, genes, and other therapeutic agents.Author: Igor I. Slowing, Juan L. Vivero-Escoto, Chia-Wen Wu, Victor S.-Y. Lin
https://pubs.acs.org/doi/abs/10.1021/ja901831u
A boronic acid-functionalized mesoporous silica nanoparticle-based drug delivery system (BA-MSN) for glucose-responsive controlled release of both insulin and cyclic adenosine monophosphate (cAMP) was synthesized. Fluorescein isothiocyanate-labeled, gluconic acid-modified insulin (FITC-G-Ins) proteins were immobilized on the exterior surface of BA-MSN and also served as caps to encapsulate ...Author: Yannan Zhao, Brian G. Trewyn, Igor I. Slowing, Victor S.-Y. Lin
https://www.researchgate.net/publication/335661321_Mesoporous_Silica_Nanoparticles_for_Drug_Delivery
The application of mesoporous silica nanoparticles as a platform for drug delivery and bioimaging requires a good understanding of the degradability of these particles under physiological conditions.
https://pubs.rsc.org/en/content/articlelanding/2011/jm/c0jm03851b
The biomedical applications of mesoporous silica nanoparticles (MSNs) as efficient drug delivery carriers have attracted great attention in the last decade. The structure, morphology, size, and surface properties of MSNs have been found to be facilely tunable for the purposes of drug loading, controlled drug release and delivery, and multifuctionalization.Author: Qianjun He, Jianlin Shi
https://www.researchgate.net/publication/320267311_Mesoporous_Silica_Nanoparticles_for_Drug_Delivery_and_Controlled_Release
PDF Drug molecules with lack of specificity and solubility lead patients to take high doses of the drug to achieve sufficient therapeutic effects.... Find, read and cite all the research you ...
http://web.ics.purdue.edu/~jfleary/nanomedicine_course_2011/Lecture_5%20Core%20materials/Lecture%205%20References/Slowing_Mesoporous_NP_drug%20delivery-sensing.pdf
the pore and particle morphology of the mesoporous silica materials would have an impact on the controlled release properties. In order to address that question we developed a room-temperature ionic liquid (RTIL)-templated MSN system [10], I. I. Slowing et al./Mesoporous Silica Nanoparticles for Drug Delivery and Biosensing Applications
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