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https://www.researchgate.net/publication/234058157_Mesoporous_silica_An_alternative_diffusion_controlled_drug_delivery_system
Mesoporous silica: An alternative diffusion controlled drug delivery system ... some examples are given on different mesoporous silica systems as drug delivery devices and how factors such as pore ...
https://www.onlinelibrary.wiley.com/doi/abs/10.1002/wnan.13
Nov 20, 2008 · Mesoporous silica‐based nanomaterials for drug delivery: evaluation of structural properties associated with release rate. Maria Strømme. ... a study of the controlled release of amino acid‐derived amphiphilic molecules from the internal pore structure of mesoporous nanoparticle drug delivery systems with different structural properties ...
https://pubs.rsc.org/en/content/articlelanding/2017/cs/c7cs00219j#!
Conventional cancer chemotherapy is often associated with toxicity issues. Thus, new drug delivery systems (DDSs) are developed as alternatives owing to their potential to selectively target affected cells while sparing normal tissues. Among them, noninvasive and biocompatible mesoporous silica …
https://www.sigmaaldrich.com/technical-documents/articles/materials-science/renewable-alternative-energy/mesoporous-silica.html
The release of drug from the silica carrier is a key performance indicator to consider when employing OMMs (ordered mesoporous materials) for drug dissolution enhancement. The in vitro release of drug from drug–silica samples and the dissolution of the starting fenofibrate are shown in Figure 6.
https://www.nature.com/articles/s41598-020-63015-6
The diffusion coefficients K 1 of the fitting equations were between 0.45~1 controlled by a non-Fickian diffusion ... drug release process of mesoporous silica was illustrated by characterization ...
https://www.researchgate.net/profile/Igor_Slowing/publication/6171403_Mesoporous_Silica_Nanoparticle_Based_Controlled_Release_Drug_Delivery_and_Biosensor_Systems/links/572b721108aef7c7e2c6b2d5.pdf?origin=publication_detail
Mesoporous silica nanoparticle based controlled release, drug delivery, and biosensor systems Brian G. Trewyn, Supratim Giri, Igor I. Slowing and Victor S.-Y. Lin *
https://www.mdpi.com/2073-4360/12/4/888/htm
There have been numerous examples of nanocarriers composed of thermoresponsive polymers that can be applied for releasing active substances using either temperature-triggered or other types of mechanisms [23,24,25,26,27].One may observe also a growing interest concerning mechanized silica nanoparticles that utilize supramolecular nanovalves responding to external stimuli for controlled …
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-020-00608-3
Recently, mesoporous silica nanoparticles have drawn the attention as carrier system for the topical delivery of active chemical compounds because of their unique properties such as extremely high surface area, ordered porosity, and tunable pore volume [16, 17]. Therefore development of mesoporous silica nanoparticles drug-delivery systems ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969802/
Jan 09, 2014 · In the fight against cancer, controlled drug delivery systems have emerged to enhance the therapeutic efficacy and safety of anti-cancer drugs. Among these systems, mesoporous silica nanoparticles (MSNs) with a functional surface possess obvious advantages and were thus rapidly developed for cancer treatment.
https://pubs.acs.org/doi/abs/10.1021/acs.langmuir.6b00214
The selective action of drugs in tumor cells is a major problem in cancer therapy. Most chemotherapy drugs act nonspecifically and damage both cancer and healthy cells causing various side effects. In this study, the preparation of a selective drug delivery system, which is able to act as a carrier for hydrophobic and anticancer drugs is reported.
https://www.researchgate.net/publication/319908495_Mesoporous_Silica_Nanoparticles_A_Review
Eventually the conventional MSNs can hold upto 200-300mg drug inside; however, hollow-core-mesoporous shell structure is able to hold more drug inside i.e., >1 g drug/1 g of silica [19]. ...
https://www.slideshare.net/VAMSIKATTA1/mesoporous-materialsdrug-delivery
Nov 13, 2015 · Over View of Present Research Work on Mesoporous Materials for Drug Delivery: Owing to high chemical and thermal stabilities, large surface areas and good compatibilities with other materials, porous silica has also found wide application in adsorption, enzyme immobilization and drug delivery. On the basis of silica-embedding and ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943960/
Dec 25, 2017 · This manuscript reviews the recent progress on mesoporous silica nanoparticles as drug delivery systems. Their intrinsic structural, textural and chemical features permit to design versatile multifunctional nanosystems with the capability to target the diseased tissue and release the cargo on demand upon exposition to internal or external stimuli.
https://www.researchgate.net/publication/326465453_Applications_of_mesoporous_silica_in_biosensing_and_controlled_release_of_insulin
Keywords: mesoporous silica nanoparticle, drug delivery system, controlled release, stimuli-responsive, chemotherapy View Show abstract A review on the strategies for oral delivery of …
https://pubs.acs.org/doi/10.1021/acsabm.9b00895
Injected tissue-affinity drug-laden nanocomposite hydrogels are promising materials for tumor therapy owing to both maintenance and release of drug in situ. In this study, a hyaluronic acid (HA) hydrogel covalently embedded with doxorubicin loaded and triphenylphosphine (TPP) modified core–shell gold mesoporous silica nanoparticles is fabricated as a local drug-delivery system for sustained ...
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