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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522861/
Targeted drug delivery of mesoporous silica nanoparticles. Specific targeting is highly attractive as an approach to spontaneously distinguish the site of disease diagnosis and as a result, this technique reduces drug administration dosage and diminishes toxic side-effects of drugs during circulation.
https://onlinelibrary.wiley.com/doi/full/10.1002/anie.200604488
Sep 28, 2007 · Research on mesoporous materials for biomedical purposes has experienced an outstanding increase during recent years. Since 2001, when MCM‐41 was first proposed as drug‐delivery system, silica‐based materials, such as SBA‐15 or MCM‐48, and some metal–organic frameworks have been discussed as drug carriers and controlled‐release systems.Author: María Vallet-Regí, Francisco Balas, Daniel Arcos
https://meddocsonline.org/ebooks/ebook-nanotechnology/Applications_of_Mesoporous_Material_for_Drug_Delivery.pdf
Their potentiality in drug delivery system was scientifically studied and reported in the literature. [11-13]. The important features of these materials are great opportu- ... Mesoporous materials are synthesized by a variety of or-ganic, inorganic or mixture of organic and inorganic compounds
https://www.sciencedirect.com/science/article/pii/S1387181108003302
Drug delivery polymers that are responsive toward several types of stimulants, such as temperature, pH, and magnetic/electric field have been reported . For drug/mesoporous silica system, several similar strategies for stimuli-responsive controlled-release have also been tested.Author: Shaobin Wang
https://onlinelibrary.wiley.com/doi/abs/10.1002/adfm.201902634
Among all the available nanoparticles, inorganic mesoporous silica nanoparticles are the newcomers to the field, contributing with their unique and superlative properties. A brief overview of the most recent progress in the synthesis of mesoporous silica nanoparticles and …Author: Miguel Manzano, Miguel Manzano, María Vallet‐Regí, María Vallet‐Regí
https://www.sciencedirect.com/science/article/pii/S1387181120301189
Mesoporous silica nanoparticles are versatile platforms for drug delivery purposes. • Mesoporous silica nanoparticles size and morphology affect their biocompatibility. • Sealing the mesopores with capping agents prevent pre-mature and off-target release. • Smart mesoporous silica nanoparticles respond to stimuli to unlade the cargo.Author: Amirala Bakhshian Nik, Hossein Zare, Seyedsahameddin Razavi, Hesameddin Mohammadi, Pooya Torab Ahmad...
https://pubs.acs.org/doi/10.1021/am403999q
A major challenge for a drug-delivery system is to engineer stable drug carriers with excellent biocompatibility, monodisperse size, and controllable release profiles. In this study, we used a microfluidic technique to encapsulate thermally hydrocarbonized porous silicon (THCPSi) microparticles within solid lipid microparticles (SLMs) to overcome the drawbacks accompanied by THCPSi ...Author: Dongfei Liu, Bárbara Herranz-Blanco, Ermei Mäkilä, Laura R. Arriaga, Sabiruddin Mirza, David A. Weit...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943960/
Dec 25, 2017 · This manuscript reviews the recent progress on mesoporous silica nanoparticles as drug delivery systems. Their intrinsic structural, textural and chemical features permit to design versatile multifunctional nanosystems with the capability to target the diseased tissue and release the cargo on demand upon exposition to internal or external stimuli.Author: María Vallet-Regí, Montserrat Colilla, Isabel Izquierdo-Barba, Miguel Manzano
https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/chem.201500578
The ever‐growing interest for finding efficient and reliable methods for treatment of diseases has set a precedent for the design and synthesis of new functional hybrid materials, namely porous nanoparticles, for controlled drug delivery. Mesoporous silica nanoparticles (MSNPs) represent one of the most promising nanocarriers for drug ...
http://web.ics.purdue.edu/~jfleary/nanomedicine_course_2011/Lecture_5%20Core%20materials/Lecture%205%20References/Slowing_Mesoporous_NP_drug%20delivery-sensing.pdf
Mesoporous Silica Nanoparticles for Drug Delivery and Biosensing Applications** By Igor I. Slowing, Brian G. Trewyn, Supratim Giri, and Victor S.-Y. Lin* 1. Introduction Recent breakthroughs in the synthesis of mesoporous silica materials with controlled particle size, morphology, and porosi-ty, along with their chemical stability, has made ...
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