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https://www.sciencedirect.com/science/article/pii/S0169409X17302429
Liu, et al. devised a refillable MEMS drug delivery device which consisted of electrodes for actuation, a drug reservoir, and a cannula . Metal electrodes for the actuation were fabricated on a silicon wafer while the 10-mm-long, 10-mm-wide, and 2-mm-thick drug reservoir was fabricated using an SU-8 photoresist.Author: Hyunjoo J. Lee, Nakwon Choi, Nakwon Choi, Eui-Sung Yoon, Il-Joo Cho, Il-Joo Cho
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348997/
With the adjustability in flow rate offered by our system, a multitude of pharmacodynamic responses can be studied in a way that has not been possible until now. We also demonstrate, for the first time, an implantable MEMS micropump system for controlled dose, timing, and location of drug delivery in mice.Author: Heidi Gensler, Roya Sheybani, Po-Ying Li, Ronalee Lo Mann, Ellis Meng
https://www.technologyreview.com/s/409122/delivering-drugs-with-mems/
Nov 30, 2007 · An MIT spinoff is finally ready to begin testing smart implants for drug delivery and sensing. skip to main content ... Delivering Drugs with MEMS. …
http://biomems.usc.edu/publications/2009/2009_BioMicroDev_ocular_drug_delivery.pdf
A passive MEMS drug delivery pump for treatment of ocular diseases Ronalee Lo & Po-Ying Li & Saloomeh Saati & Rajat N. Agrawal & Mark S. Humayun & Ellis Meng # Springer Science + Business Media, LLC 2009 Abstract An implantable manually-actuated drug delivery
https://www.sciencedirect.com/science/article/abs/pii/S0169409X17302429
MEMS devices for drug delivery ... Novel drug delivery systems based on microtechnology have advanced tremendously, but yet face some technological and societal hurdles to fully achieve their potential. The novel drug delivery systems aim to deliver drugs in a spatiotemporal- and dosage-controlled manner with a goal to address the unmet medical ...Author: Hyunjoo J. Lee, Nakwon Choi, Nakwon Choi, Eui-Sung Yoon, Il-Joo Cho, Il-Joo Cho
http://clifton.mech.northwestern.edu/~me381/project/done/BioMEMS.pdf
Typical delivery methods include hypodermics and pills, which can be invasive and difficult to control. Efforts have been made to find drug delivery methods that are both minimally invasive and allow control of the delivery site and amount. Microelectromechanical system (MEMS) devices offer a solution to both of these shortcomings.
https://www.ncbi.nlm.nih.gov/pubmed/25703045
Microelectromechanical systems (MEMS) technologies have allowed the development of advanced miniaturized devices for medical and biological applications. This Review presents the use of MEMS technologies to produce drug delivery devices detailing the delivery mechanisms, device formats employed, and various biomedical applications.Author: Angelica Cobo, Roya Sheybani, Ellis Meng
https://www.microchip.com/design-centers/medical/applications/medical-drug-delivery-pumps/design-files-demo-boards/medical-mems-pump-demo
MEMS piezoelectric micro pumps offer an attractive alternative to standard pumps that have traditionally been used in precision controlled drug delivery devices. MEMS piezoelectric micro pumps offer the benefits of being small, lightweight, low power, low cost and accurate.
https://www.microchip.com/design-centers/medical/applications/medical-drug-delivery-pumps
A relatively new type of medical drug delivery pump is the MEMS piezoelectric micro pump. This type of pump offers an attractive alternative to standard pumps that have traditionally been used in precision controlled drug delivery devices, such as infusion pumps, insulin pumps or nebulizers.
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