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https://medical-dictionary.thefreedictionary.com/MedPulser
MedPulser: A device for delivering electroporation-enhanced delivery of drugs, DNA vaccines and gene therapies intended to treat cancer, infectious diseases and other medical conditions. Adverse effects Pain, occurring within five minutes of electroporation.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835142/
Apr 30, 2009 · Tolerability of Two Sequential Electroporation Treatments Using MedPulser DNA Delivery System (DDS) in Healthy Adults Mark Wallace , 1 Barbara Evans , 2 Sandra Woods , 1 Robin Mogg , 2 Lei Zhang , 3 Adam C Finnefrock , 2 Dietmar Rabussay , 3 Michael Fons , 3 John Mallee , 2 Devan Mehrotra , 2 Florian Schödel , 2 and Luwy Musey 2Author: Mark Wallace, Barbara Evans, Sandra Woods, Robin Mogg, Lei Zhang, Adam C Finnefrock, Dietmar Rabussa...
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(16)31793-2
DNA vaccination using the MedPulser DNA Delivery System in rhesus macaques: Development of clinical electroporation parameters. 2008. Google Scholar; The present study evaluates the tolerability of repeated treatments with the MedPulser DDS in healthy adults. Assessment of pain experience was based on patient self-report using two clinically ...Author: Mark Wallace, Barbara Evans, Sandra Woods, Robin Mogg, Lei Zhang, Adam C Finnefrock, Dietmar Rabussa...
https://www.sciencedirect.com/science/article/pii/S1525001616317932
Tolerability of Two Sequential Electroporation Treatments Using MedPulser DNA Delivery System (DDS) in Healthy Adults ... An earlier version of the device, called the MedPulser electroporation therapy system, is currently being used in cancer patients for the intratumoral delivery of …Author: Mark Wallace, Barbara Evans, Sandra Woods, Robin Mogg, Lei Zhang, Adam C Finnefrock, Dietmar Rabussa...
http://ir.inovio.com/news-and-media/news/press-release-details/2005/Inovio-Biomedical-Receives-Milestone-Payment-from-Merck-Regarding-MedPulser-DNA-Delivery-System/default.aspx
Jul 13, 2005 · SAN DIEGO--(BUSINESS WIRE)--July 13, 2005--Inovio Biomedical Corporation (AMEX:INO) announced today that it will receive a $2 million milestone payment from Merck & Co., Inc. (NYSE:MRK) resulting from the achievement of a clinical milestone by Merck for a plasmid-based vaccine using Inovio's MedPulser® DNA Delivery System.
http://ir.inovio.com/news-and-media/news/press-release-details/2004/Gentronics-and-Merck-Sign-Licensing-Agreement-for-MedPulser-DNA-Delivery-System-to-Support-DNA-Vaccine-Delivery/default.aspx
May 24, 2004 · SAN DIEGO, CA, May 24, 2004 - Genetronics Biomedical Corporation (AMEX: GEB) has signed a collaboration and licensing agreement with Merck & Co., Inc. (NYSE: MRK) to develop and commercialize Genetronics' MedPulser® DNA Delivery System, which will be developed for use with certain of Merck's DNA vaccine programs. This development and commercialization agreement is an …
https://www.researchgate.net/publication/24192122_Tolerability_of_Two_Sequential_Electroporation_Treatments_Using_MedPulser_DNA_Delivery_System_DDS_in_Healthy_Adults
Tolerability of Two Sequential Electroporation Treatments Using MedPulser DNA Delivery System (DDS) in Healthy Adults.pdf Available via license: CC BY-NC …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109217/
Electroporation Enhanced DNA Vaccine Delivery. Electroporation (EP) is a method to introduce macromolecules such as nucleic acids into cells, either in vivo or in vitro, via the application of brief electric pulses to induce transient and reversible permeabilization of the cell membrane (Figure 1).Over the last decade the technique has evolved from an experimental technique to now being used ...Author: Niranjan Y Sardesai, David B Weiner
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