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https://pubs.acs.org/doi/abs/10.1021/cm0011559
A new application of MCM-41 mesoporous materials has been developed. Two kinds of surfactants, C16TAB and C12TAB, have been employed to get different pore sizes. The samples were disk-shaped conformed before and after charging with ibuprofen, an anti-inflammatory drug. In all the cases the weight percent ratio of drug/MCM-41 was 30%.Author: M. Vallet-Regi, A. Rámila, and R. P. del Real, J. Pérez-Pariente
https://pubs.acs.org/doi/10.1021/cm021217q
Dec 21, 2002 · Organic modification with aminopropyl group of two MCM-41 materials having different pore sizes (obtained from trimethylalkylammonium surfactants with different chain sizes (16 and 12 carbon atoms)) has been carried out in order to control the delivery rate of ibuprofen from the siliceous matrix. This functionalization was performed by two different methods: the as-synthesized MCM-41 …Author: B. Muñoz, A. Rámila, J. Pérez-Pariente, and I. Díaz, M. Vallet-Regí
https://www.sciencedirect.com/science/article/pii/S1385894707005232
Drug delivery is faster in the initial testing time and achieves a stationary state after around 48 h, for pure silica samples and 150 h for functionalized MCM-41.Author: M. Manzano, V. Aina, C. Arean, F. Balas, Valentina Alice Cauda, M. Colilla, M. Delgado, M. Vallet-Re...
https://dergipark.org.tr/tr/download/article-file/638847
mesopoous silicates, the MCM-41 has a high specific surface area (~ 1150 m2/g), a larger pore volume (~ 1 cm3/g), and smaller pore size (2-5 nm), thus being a drug carrier. MCM-41 has attracted more attention as a carrier for drug delivery (2). MCM has been tested for the transport and controlled release of …Author: Fatih Mehmet Emen, Ruken Esra Demirdöğen, Göktürk Avşar, Derya Kiliç
https://www.researchgate.net/publication/231235779_A_new_property_of_MCM-41_Drug_delivery_system
In particular, mesoporous silicate MCM-41, which has an amorphous structure, is one of the most widely used mesoporous material and has potential application in drug delivery, in which water plays...
https://www.researchgate.net/publication/224863195_Studies_on_MCM-41_Mesoporous_Silica_for_Drug_Delivery_Effect_of_Particle_Morphology_and_Amine_Functionalization
For the purpose of testing the effect of carrier morphology on drug delivery rate, MCM-41 was prepared in the form of both, a powder consisting of irregularly shaped (and sized) particles and...
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