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https://www.farmavita.net/documents/Matrix%20Drug%20Delivery%20System.pdf
No .4. Diffusion controlled devices – (a) rigid matrix, and (b) swellable matrix. In this system, a solid drug is dispersed in lipophillic or a hydrophilic polymer matrix and the rate of release of drug depends on the rate of drug diffusion and not on the rate of solid dissolution.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648939/
Nov 04, 2012 · Hydrophilic matrix systems tend to be more popular in tablet manufacture for controlled release drug delivery systems due to their low manufacturing cost (Tiwari 2003). On contact with water a hydrophilic matrix increases in size due to the entry of the solvent. This then allows the polymer to swell up forming a barrier to drug release.Author: Ali Nokhodchi, Shaista Raja, Pryia Patel, Kofi Asare-Addo
https://www.researchgate.net/publication/323006062_MATRIX_DRUG_DELIVERY_SYSTEM_A_REVIEW
matrix drug delivery system: a review B. Deepika* 1 , Sobana Sam een 1 , Najmu saher Nazneen 1 , A. Madhavi 1 , Kandukoori Naga R aju 1 , KNV Rao 2 and K. Rajeswar Dutt 3
http://jpsbr.org/index_htm_files/3_1151.pdf
sustained release or controlled release drug delivery systems. 11 Matrix systems are widely used for the purpose of sustained release. It is the release system which prolongs and controls the release of the drug that is dissolved or dispersed. In fact, a matrix is defined as a well-mixed composite of one or moreFile Size: 679KB
http://www.authorstream.com/Presentation/amitmgupta31-149658-control-drug-delivery-system-amit-gupta-education-ppt-powerpoint/
Feb 11, 2009 · Sustained drug delivery system : Sustained drug delivery system Simply prolong the drug release Plasma drug level for extended period of time Not necessarily at predetermined time rate Reduce dosing frequency Uniform plasma concentration at steady–state.
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