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https://d-nb.info/1024784770/34
MATRIX- AND RESERVOIR-TYPE ORAL MULTIPARTICULATE DRUG DELIVERY SYSTEMS Dissertation zur Erlangung des akademischen Grades des Doktors der Naturwissenschaften (Dr. rer. nat.) eingereicht im Fachbereich Biologie, Chemie, Pharmazie der Freien Universität Berlin vorgelegt von JOANA MOTA Portugal Berlin, 2010
https://www.sciencedirect.com/science/article/pii/S1740674918300040
Herein, we presented a general review on oral matrix systems, summarizing the possible technologies to develop both hydrophilic and inert matrices. Oral administration of medications is the most convenient route, however drug delivery from a matrix is an effective and finally safe choice for parenteral administration as well.Author: Gábor Vasvári, József Kalmár, Péter Veres, Miklós Vecsernyés, Ildikó Bácskay, Pálma Fehér, Zoltán Uj...
https://www.hansvanlaarhoven.nl/reservoir-system/
In a reservoir system the drug is either molecular dissolved or dispersed in a reservoir that is surrounded by a rate limiting inert membrane. In a monolithic or matrix device this membrane is absent. Although controlled delivery from a monolithic device is very well possible, the presence of a membrane normally provides for a better release profile.
https://www.researchgate.net/publication/326577771_Matrix_systems_for_oral_drug_delivery_Formulations_and_drug_release
In this current article matrix formulations for oral drug delivery are reviewed. Conventional dosage forms and novel applications such as 3D printed matrices and aerogel matrices are discussed.
https://www.researchgate.net/publication/323006062_MATRIX_DRUG_DELIVERY_SYSTEM_A_REVIEW
In particular oral drug delivery has been the focus of pharmaceutical research for many years. This type of drug delivery has been at the centre of research due to its many benefits over conventional dosage. The focus of this review is on matrix tablets due to their widely use and simplicity of the formulation.
http://jpsbr.org/index_htm_files/3_1151.pdf
sustained release or controlled release drug delivery systems. 11 Matrix systems are widely used for the purpose of sustained release. It is the release system which prolongs and controls the release of the drug that is dissolved or dispersed. In fact, a matrix is defined as a well-mixed composite …File Size: 679KB
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648939/
Nov 04, 2012 · Hydrophillic matrix systems are among the most commonly used means for oral controlled drug delivery as they can reproduce a desirable drug profile and are cost effective (Prajapati and Patel 2010, The Dow Chemical Company 2000).Author: Ali Nokhodchi, Shaista Raja, Pryia Patel, Kofi Asare-Addo
https://www.pharma-iq.com/pre-clinical-discovery-and-development/articles/multiparticulate-drug-delivery-systems
Multiparticulates can be administered by parenteral or oral route. But, traditionally oral route is the most preferred route of administration by the patients. These multiparticulates can be administered orally in capsule or tablet dosage forms. Most of the multiparticulate systems available in market are present in the form of capsules.
http://www.bioline.org.br/pdf?pr08028
multiparticulate systems are to be more uniformly dispersed in the GI tract and also ensure more uniform drug absorption 3. A multiparticulate system of chitosan hydrogel beads has been investigated for colon-specific delivery of macromolecules using fluorescein is othiocyanate-labeled bovine serum albumin as a model protein 8.
https://www.pharmatutor.org/articles/oral-controlled-release-drug-delivery-system-review
A desirable characteristic of controlled release delivery system is that the duration of drug action should be dictated by the design property of drug molecules. There are different mechanistic aspects for design of oral controlled release drug delivery systems such as matrix, reservoir, osmotic pressure, ion exchange resins, altered density etc.Author: M Gahlyan, S Jain
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