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https://www.sciencedirect.com/science/article/pii/S0169409X01001168
Mathematical drug release modeling of bioerodible delivery systems is not as advanced as the modeling of diffusion or swelling-controlled devices, because it is generally more complex , , , . Besides physical mass transport phenomena, chemical reactions such as polymer chain cleavage have to be considered in bioerodible systems.Author: J. Siepmann, A. Göpferich
https://www.sciencedirect.com/science/article/abs/pii/S0169409X01001168
The aim of this article is to give an introduction into mathematical modeling approaches of bioerodible controlled drug delivery systems and to present the most important erosion theories reported in …Author: J. Siepmann, A. Göpferich
https://www.researchgate.net/publication/11969273_Mathematical_modeling_of_bioerodible_polymeric_drug_delivery_systems
The aim of this article is to give an introduction into mathematical modeling approaches of bioerodible controlled drug delivery systems and to present the most important erosion theories reported ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518665/
Jan 10, 2013 · The place of these types of models in the broader context of mathematical models for polymeric drug delivery systems is illustrated in Fig. 3. In vivo drug delivery is outside the scope of the present article, and the reader is referred to Grassi et al. for a review of mathematical models for simultaneous drug release and in vivo drug absorption.Author: Ashlee N. Ford Versypt, Ashlee N. Ford Versypt, Daniel W. Pack, Daniel W. Pack, Richard D. Braatz, R...
https://www.deepdyve.com/lp/elsevier/mathematical-modeling-of-bioerodible-polymeric-drug-delivery-systems-s3JszsYpv3
Jun 11, 2001 · Read "Mathematical modeling of bioerodible, polymeric drug delivery systems, Advanced Drug Delivery Reviews" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
https://link.springer.com/article/10.1007%2Fs42242-019-00041-y
May 15, 2019 · Transdermal drug delivery systems have overcome many limitations of other drug administration routes, such as injection pain and first-pass metabolism following oral route, although transdermal drug delivery systems are limited to drugs with low molecular weight. Hence, new emerging technology allowing high molecular weight drug delivery across the skin—known as …Author: Sarvenaz Chavoshi, Mohammad Rabiee, Mehdi Rafizadeh, Navid Rabiee, Alireza Shahin Shamsabadi, Mojtab...
https://link.springer.com/article/10.1023/A:1021457911533
Results. The new mathematical model considers drug dissolution, diffusion with nonconstant diffusivities and moving boundary conditions, polymer degradation/erosion, time-dependent system porosities, and the three-dimensional geometry of the devices. ... Mathematical modeling of bioerodible, polymeric drug delivery systems. Adv. Drug Deliv. Rev ...Author: Juergen Siepmann, Nathalie Faisant, Jean-Pierre Benoit
https://www.researchgate.net/publication/216212248_Mathematical_modelling_of_magnetically_targeted_drug_delivery
A mathematical model for targeted drug delivery using magnetic particles is developed. This includes a diffusive flux of particles arising from interactions between erythrocytes in the ...
https://pubs.acs.org/doi/full/10.1021/mp500078u?src=recsys
The present work is focused on the development and the validation of a mechanistic model describing the degradation of drug-loaded polylactic-co-glycolic acid microparticles and the drug release process from such devices. Microparticles’ degradation is described through mass conservation equations; the application of population balances allows a detailed description of the hydrolysis ...Author: Tommaso Casalini, Filippo Rossi, Stefano Lazzari, Giuseppe Perale, Maurizio Masi
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846103/
There have been several nicely written reviews on mathematical modeling for bioerodible polymeric delivery systems , dissolution controlled drug delivery systems , microsphere delivery systems and hydrogel networks . In general, diffusion, erosion, and degradation are the most important mechanisms for solute transport from polymeric matrices.Author: Yao Fu, Weiyuan John Kao
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